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Hypoxia

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Hypoxia

38 trials tracked for Hypoxia: 4 in phase 3 or 4.

38Trials tracked

4Phase 3 & 4

0Recruiting

0With published results

Phase distribution

Phase 4 2 Phase 3 2 Phase 2 3 Other / NA 31

Phase 4 Ketamine Effect After Laparoscopic Gastric Reduction: A Randomized, Double-Blinded, Placebo Controlled Study Completed
Phase 4 Effects of Nebivolol Versus Carvedilol on Cardiopulmonary Function at High Altitude in Healthy Subjects. Completed
Phase 3 Controlled Acute Hypoxia Study Comparing Pulse Oximetry to Arterial Blood Samples During Motion Completed
Phase 3 Effects of Caffeine on Intermittent Hypoxia in Infants Born Preterm Completed
Phase 2 Administration of Intravenous Vitamin C in Novel Coronavirus Infection (COVID-19) and Decreased Oxygenation Completed
Phase 2 Nebulised Dornase Alfa for Treatment of COVID-19 (Coronavirus Disease 2019) Completed

Show 32 more trials

Phase 2 Evaluation of the Attenuation by Aes-103 of Hypoxia Mediated Decrements in Endurance Exercise Performance Completed
N/A In Vivo Pulse Oximeter Validation Study Completed
N/A SpO2 Accuracy of Noninvasive Disposable Pulse Oximeter Sensor Completed
N/A The Effect of Prolonged Inspiratory Time on Pulmonary Mechanics in Obese Patients Completed
N/A Hypoxemia in the First 24 Hours After Trauma - an Observational Study Completed
N/A Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients Completed
N/A Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO19) Completed
N/A Intermittent Versus Continuous Pulse Oximetry Monitoring of Infants Admitted for Bronchiolitis Completed
N/A Positive Pressure at Induction of Anesthesia in Children Completed
N/A SpO2 Accuracy of Noninvasive Pulse Oximeter Sensor With Motion Conditions Completed
N/A Accuracy of Owlet Smart Sock Sensor 3rd Generation With Profound Hypoxia Completed
N/A The Effect of Chronic Nitrate Supplementation on Acute Mountain Sickness and Exercise Performance in Hypoxia Completed
N/A Non-invasive Intervention for Apnea of Prematurity Completed
N/A Use of Capnography in EGD and Colonoscopy With Moderate Sedation. Completed
N/A Beetroot Juice as a Potential Ergogenic Aid During Exercise in Hypoxia Completed
N/A SpO2 Accuracy of Noninvasive Pulse Oximeter Sensor Completed
N/A Accuracy of Pulse Oximeters With Profound Hypoxia at Rest Completed
N/A Accuracy of Pulse Oximeters With Profound Hypoxia During Motion Completed
N/A Effects of Cyclic Variations in Altitude Conditioning (CVAC) on Wellness and Activity Measures Completed
N/A SpO2 Accuracy Comparison of Smart Sock V. 2 SpO2 to Arterial Blood CO-Oximetry Completed
N/A SpO2 Accuracy of Noninvasive Disposable Pulse Oximeter Sensor With Motion Conditions Completed
N/A Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures Completed
N/A Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO17) Completed
N/A NICU Oxygen Control Study Completed
N/A Apneic Oxygenation During Airway Management in Pediatric Patients Completed
N/A Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO16) Completed
N/A Preoxygenation With Nasal Cannula and Noninvasive Positive Pressure Ventilation Completed
N/A Using Capnography to Reduce Hypoxia During Pediatric Sedation Completed
N/A Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO18) Completed
N/A TOBY (TOtal Body hYpothermia): a Study of Treatment for Perinatal Asphyxia Completed
N/A Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy Completed
N/A The Psychophysiological Effect of Simulated and Terrestrial Altitude Completed

Showing the 38 most-cited and recently-updated of 38 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Hypoxia: what the trials found

Clinical evaluations of pulse oximetry and related monitoring technologies are well-documented across multiple studies. Research involving various pulse oximeter models, including specific Stryker Sustainability Solutions systems, has been conducted to evaluate performance in clinical settings.

Pharmacological interventions show varying results: Caffeine citrate (6 mg/kg/day) was shown to significantly reduce the number of episodes of intermittent hypoxia per hour (p < 0.05). Ketamine was evaluated for its impact on postoperative pain scores, and placebo effects were measured in studies regarding peak exercise oxygen consumption.

Monitoring metrics such as arterial lines have been established in clinical protocols.

Recent results — preliminary, needs further review

Terrestrial altitude was investigated as an intervention (not yet corroborated).

For the clinician treating this condition

Caffeine citrate at 6 mg/kg/day is effective in reducing episodes of intermittent hypoxia.
Pulse oximetry remains a standard and frequently studied method for monitoring oxygen saturation across various hardware platforms.

AI synthesis of 0 cited trials, updated Jun 29, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.