Review proposes DC-NK metabolic checkpoint concept in viral asthma exacerbations
Why do colds hit people with asthma so hard? A new idea points to exhausted immune cells.
A systematic review synthesizes murine and in vitro evidence proposing that dendritic cell-natural killer cell metabolic dysregulation contr…
Asthma colds trigger dangerous flares because stressed immune cells create an acidic environment that exhausts the virus-fighting cells need…
Hypoxia in solid tumors drives metabolic reprogramming, immune suppression, and therapeutic resistance
How do tumors survive in low oxygen? They completely change how they eat.
A systematic review synthesizing evidence on hypoxia in solid tumors found that low oxygen tension orchestrates metabolic reprogramming thro…
When tumors run out of oxygen, they switch diets to eat fat and glutamine, becoming more invasive, acidic, and resistant to treatment.