N/A
N=60
PeLear CCC: Proyecto Latino Contra Cancer Colorrectal
Colorectal Cancer · Rectal Cancer · Colon Cancer · Colon Rectal Cancer · Rectal Neoplasms
Bottom Line
View on ClinicalTrials.gov: NCT06426927 ↗Enrolled (actual)
60
Serious AEs
—
Results posted
Jan 2026
Primary outcome: Primary: Attitudes Regarding Participation in Clinical Trials-Conceptual Themes (General Clinical Trials) — 85; 80 percentage of participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Colorectal Cancer Educational Videos in Spanish (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of North Carolina, Chapel Hill
- Primary completion
- Mar 2025
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Attitudes Regarding Participation in Clinical Trials-Conceptual Themes (General Clinical Trials) |
85; 80 | — |
| PRIMARY Attitudes Regarding Participation in Cancer Clinical Trials-Conceptual Themes (Cancer Clinical Trials) |
60; 45 | — |
| PRIMARY Perceptions of Latino Community for Increasing Enrollment in Randomized Clinical Trials-Conceptual Themes (General Clinical Trials) |
90; 80 | — |
| PRIMARY Holistic Themes |
58; 100; 45 | — |
| SECONDARY Association of Educational Videos on Knowledge of Colorectal Cancer Symptoms |
4.10; 7.23; 6.95 | <0.0001 sig |
| SECONDARY Association of Educational Videos on Knowledge of Colorectal Cancer Risk Factors |
3.06; 4.08; 3.93 | <0.0001 sig |
| SECONDARY Association of Educational Videos on Knowledge of Colorectal Cancer Screening and Facts |
3.80; 6.05; 5.12 | <0.0001 sig |
| SECONDARY Association of Watching the Video and Willingness to Participate in Cancer Clinical Trials |
55; 54 | 0.56 |
Summary
The study aims to recruit 60 Spanish speaking individuals who identify as Latinos, are 18 years or older and attend the Saint Thomas More (STM) Church in Chapel Hill. Study participants will be asked to attend an educational session at STM Church during which their baseline knowledge on colorectal cancer (CRC) and willingness to participate in cancer clinical trials (CCT) will be assessed through a questionnaire in Spanish. Following this, participants will watch three educational videos on CRC in Spanish. After watching the videos, CRC knowledge and willingness to participate in CCTs will be reassessed. Thirty +/- 7 days after participation in the educational session, participants will be invited back at STM Church in order to complete a follow-up questionnaire assessing CRC knowledge, willingness to participate in CCTs and perceived barriers preventing Latinos from participating in CCTs. Twenty of the 60 recruited participants will be asked to participate in a qualitative one-on-one interview aimed at identifying barriers preventing Latinos from participating in CCTs.
It should be noted that cancer is the leading cause of death in the United States (US) Latino community, with CRC accounting for 10% of this overall mortality. Despite this, Latinos suffer from disparities in access to care, cancer screening, treatment, and representation in CCTs. In fact, although Latino individuals are among the largest and fastest growing communities of color in the US, currently comprising 18.7%, their representation in CCTs remains low. This is of concern because: 1) advances arising from trials with limited Latino representation may not be applicable to the Latino population, and 2) decreased Latino participation in CCTs may delay Latino access to novel therapies in a timely fashion. The investigators conducting this study believe that low cancer-specific health knowledge may be impacting Latino representation and willingness to participate in CCTs and can be addressed through culturally and linguistically appropriate community-based educational interventions. Latino CCT underrepresentation is a multifaceted phenomenon and bidirectional barriers at the physician-, healthcare system-, and patient-level are significant contributors. Therefore, understanding the multiple driving forces and barriers is essential to identifying potential targets for improvement.
Eligibility Criteria
Inclusion Criteria
- Spanish speaking
- Identifying as Latino
- 18 years or older
Exclusion Criteria
- Non-Spanish speakers
- Not identifying as Latino
- Younger than 18 years old
Data sourced from ClinicalTrials.gov (NCT06426927). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.