N/A
N=219
Antibiotic Prophylaxis in Percutaneous Nephrostomy Placements and Replacements for Malignant Urinary Tract Obstruction
Ureteral Obstruction · Neoplasms · Acute Kidney Injury · Nephrostomy; Complications · Antibiotic Prophylaxis
Bottom Line
View on ClinicalTrials.gov: NCT06801405 ↗Enrolled (actual)
219
Serious AEs
0.0%
Results posted
May 2026
Primary outcome: Primary: Urinary Tract Infection After Percutaneous Nephrostomy Procedure — 5; 10 Percutaneous nephrostomy procedure — p=0.548
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- antibiotic prophylaxis (Drug)
- Age
- Pediatric, Adult, Older Adult
- Sex
- All
- Sponsor
- Barretos Cancer Hospital
- Primary completion
- Oct 2024
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Urinary Tract Infection After Percutaneous Nephrostomy Procedure |
5; 10 | 0.548 |
Summary
This study aims to find out whether taking antibiotics to prevent a urinary tract infection after a medical procedure called percutaneous nephrostomy (placement of a catheter directly into the kidney to keep it working after the urinary tract has been blocked by a malignant tumour) actually prevents a urinary tract infection, compared to not taking antibiotic prophylaxis.
Eligibility Criteria
Inclusion Criteria
- Patients treated for cancer who required percutaneous nephrostomies
Exclusion Criteria
- Patients and/or procedures if percutaneous nephrostomy was used to perform other procedures;
- Patients and/or procedures if percutaneous nephrostomy was used to treat clinical conditions other than malignant ureteral obstruction
- Patients and/or procedures if percutaneous nephrostomy was used to clear the urinary tract of non-malignant causes
Data sourced from ClinicalTrials.gov (NCT06801405). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.