N/A
Completed N=219
Antibiotic Prophylaxis in Percutaneous Nephrostomy Placements and Replacements for Malignant Urinary Tract Obstruction
Ureteral Obstruction · Neoplasms · Chronic Kidney Disease · Nephrostomy; Complications
Source: ClinicalTrials.gov NCT06801405 ↗
Enrolled (actual)
219
Serious AEs
0.0%
Results posted
May 2026
Primary outcomePrimary: Urinary Tract Infection After Percutaneous Nephrostomy Procedure — 5; 10 Percutaneous nephrostomy procedure — p=0.548
Summary
This study aims to find out whether taking antibiotics to prevent a urinary tract infection after a medical procedure called percutaneous nephrostomy (placement of a catheter directly into the kidney to keep it working after the urinary tract has been blocked by a malignant tumour) actually prevents a urinary tract infection, compared to not taking antibiotic prophylaxis.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Urinary Tract Infection After Percutaneous Nephrostomy Procedure |
5; 10 | 0.548 |
Eligibility Criteria
Inclusion Criteria
- Patients treated for cancer who required percutaneous nephrostomies
Exclusion Criteria
- Patients and/or procedures if percutaneous nephrostomy was used to perform other procedures;
- Patients and/or procedures if percutaneous nephrostomy was used to treat clinical conditions other than malignant ureteral obstruction
- Patients and/or procedures if percutaneous nephrostomy was used to clear the urinary tract of non-malignant causes
Data sourced from ClinicalTrials.gov (NCT06801405). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.