N/A Completed N=168

Predicting Mortality in Patients With Return of Spontaneous Circulation After Cardiac Arrest

Post-Resuscitation Syndrome · Critical Illness · Cardiac Arrest · hypoxic-ischemic encephalopathy

Source: ClinicalTrials.gov NCT07020091 ↗

Enrolled (actual)

168

Serious AEs

0.0%

Results posted

May 2026

Primary outcomePrimary: 30-Day Mortality — 112 participants

Summary

This retrospective observational cohort study aims to identify early predictors of short- and mid-term mortality in adult patients who achieved return of spontaneous circulation (ROSC) after cardiac arrest. Eligible patients admitted to the intensive care unit between January 1, 2024 and May 31, 2025 were identified retrospectively from electronic medical records following institutional ethics approval. Clinical, biochemical, and resuscitation-related parameters recorded within the first 24 hours of ICU admission were analyzed. The primary objective was to determine factors independently associated with short-term mortality. Six-month mortality was additionally assessed using hospital records and the national death registry. The findings are expected to improve risk stratification and clinical decision-making in post-cardiac arrest care.

Outcome Measures

Outcome	Result	p-value
PRIMARY 30-Day Mortality	112	—
SECONDARY In-Hospital Mortality	87	—
SECONDARY 6-Month Mortality	130	—

Eligibility Criteria

Inclusion Criteria

Age ≥ 18 years
Achieved return of spontaneous circulation (ROSC) after cardiac arrest
Admitted to the intensive care unit (ICU)
Informed consent obtained from patient or legal representative (if applicable)

Exclusion Criteria

Age < 18 years
Known pregnancy
Brain death at the time of ICU admission
Patients with missing key clinical or laboratory data
Declined participation or legal refusal

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT07020091). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.