N/A
N=168
Predicting Mortality in Patients With Return of Spontaneous Circulation After Cardiac Arrest
Post-Resuscitation Syndrome · Critical Illness · Cardiac Arrest · Hypoxic-Ischemic Encephalopathy · Coma
Bottom Line
View on ClinicalTrials.gov: NCT07020091 ↗Enrolled (actual)
168
Serious AEs
0.0%
Results posted
May 2026
Primary outcome: Primary: 30-Day Mortality — 112 participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Ahmet Düzgün
- Primary completion
- Dec 2025
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY 30-Day Mortality |
112 | — |
| SECONDARY In-Hospital Mortality |
87 | — |
| SECONDARY 6-Month Mortality |
130 | — |
Summary
This retrospective observational cohort study aims to identify early predictors of short- and mid-term mortality in adult patients who achieved return of spontaneous circulation (ROSC) after cardiac arrest. Eligible patients admitted to the intensive care unit between January 1, 2024 and May 31, 2025 were identified retrospectively from electronic medical records following institutional ethics approval. Clinical, biochemical, and resuscitation-related parameters recorded within the first 24 hours of ICU admission were analyzed. The primary objective was to determine factors independently associated with short-term mortality. Six-month mortality was additionally assessed using hospital records and the national death registry. The findings are expected to improve risk stratification and clinical decision-making in post-cardiac arrest care.
Eligibility Criteria
Inclusion Criteria
- Age ≥ 18 years
- Achieved return of spontaneous circulation (ROSC) after cardiac arrest
- Admitted to the intensive care unit (ICU)
- Informed consent obtained from patient or legal representative (if applicable)
Exclusion Criteria
- Age < 18 years
- Known pregnancy
- Brain death at the time of ICU admission
- Patients with missing key clinical or laboratory data
- Declined participation or legal refusal
Data sourced from ClinicalTrials.gov (NCT07020091). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.