Phase 2 N=48 Ubiquinol as a Metabolic Resuscitator in Post-Cardiac Arrest
Cardiac Arrest
Primary: Coenzyme Q10 Plasma Levels — 185; 207; 113; 441 ng/mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=168 Predicting Mortality in Patients With Return of Spontaneous Circulation After Cardiac Arrest
Post-Resuscitation Syndrome · Critical Illness · Cardiac Arrest
Primary: 30-Day Mortality — 112 participants
Phase 2 N=50 Corticosteroid Therapy in Refractory Shock Following Cardiac Arrest
Cardiac Arrest
Primary: Time to Shock Reversal — 55; 49 hours
N/A N=30 Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot
Cardiac Arrest
Primary: Attrition — 0; 0 Participants
Phase 2 N=10 Coenzyme Q10 in Post-Cardiac Arrest Cerebral Resuscitation
Cardiac Arrest · Sudden Cardiac Arrest
Primary: Prevalence of Low Serum CoQ10 Levels in Cardiac Arrest Patients — 0.706; 0.66 ug/mL
N/A N=96 Effect of Epinephrine/ Phenylephrine for Preventing the Postreperfusion Syndrome During Reperfusion in Liver Transplantation
Hypotension After Reperfusion in Liver Transplantation
Primary: Occurrence of Postreperfusion Syndrome (PRS) — 45; 39; 87 percentage of participants
N/A N=22 Microcirculatory Perfusion in Patients With Coma After Out-of-hospital Cardiac Arrest
Cardiac Arrest
Primary: Microvascular Flow Index (MFI) — 1.7; 1.1 units on a scale
Phase 1 N=16 Reoxygenation After Cardiac Arrest II (REOX II Study)
Cardiac Arrest
Primary: Plasma Isofurans (pg/mL)/Isoprostanes (pg/mL) Ratio
Phase 2 N=100 Physiologic Effects of Steroids in Cardiac Arrest
Inhospital Cardiac Arrest
Primary: Early Postresuscitation Arterial Blood Pressure (mmHg) Measured Through Institution of Invasive Intra-arterial Pressure Monitoring (as Feasible). — 78.4; 75.1 mmHg…
N/A N=466 Mobile Critical Care Recovery Program for Acute Respiratory Failure Survivors
Acute Respiratory Failure · Post-Intensive Care Syndrome
Primary: Self Reported Quality of Life PCS: Physical Component Score at 1 Year — 36.22; 35.29 score on a scale
N/A N=120 Treatment of Critical Illness Polyneuromyopathy
Acute Respiratory Failure
Primary: The Primary Outcome Variable for This Study Will be the Short Form of the Continuous Scale Physical Functional Performance Test (CS-PFP) Called the PFP-10 — 19.0; 20.9…
N/A N=5 Biological Response of Trauma Patients to Standard Trauma Resuscitation Therapy
Hemorrhagic Shock
Primary: Biological Response as Characterized by Selected Cytokines, Specifically Tumor Necrosis Factor Alpha (TNFα), Interleukin One (IL-1β), and Interleukin Six (IL-6).
N/A N=15 ECPR for Refractory Out-Of-Hospital Cardiac Arrest
Cardiac Arrest · Heart Arrest · Sudden Cardiac Arrest
Primary: Emergency Department Arrivals Under 30 Minutes — 5 Participants
N/A N=99 Platelet Function in Resuscitated Patients
Acute ST Segment Elevation Myocardial Infarction
Primary: Platelet Inhibition Measured With Optical Aggregometry — 109; 253.8 AU*min
N/A N=751 Protocolized Post-Extubation Respiratory Support Study
Mechanical Ventilation Complication · Acute Respiratory Failure · Intubation Complication
Primary: Reintubation — 57; 52 Participants
N/A N=329 Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] Trial
Cardiac Arrest
Primary: Survival With Good Neurobehavioral Outcome — 48; 48; 85; 76 Participants — p=0.63
Phase 3 N=295 Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-OH [Out of Hospital] Trial
Cardiac Arrest
Primary: Survival With Good Neurobehavioral Outcome — 27; 15; 111; 107 Participants — p=0.14
N/A N=28 Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest
Cardiopulmonary Arrest · Pediatric ALL · Resuscitation
Primary: Median Alveolar Ventilation — 276; 370 ml
Phase 3 N=501 Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest
Heart Arrest
Primary: Number of Participants With Return of Spontaneous Circulation — 100; 86 participants
N/A N=626 Remote Ischaemic Postconditioning in the Clinical Setting of NSTEACS and Urgent PCI
Post Procedural Myocardial Infarction
Primary: Peri-Procedural Myocardial Injury — 23; 29 Participants
N/A N=542 A Pilot Study of Intra-arrest Therapeutic Hypothermia in Patients Suffering Non-Traumatic Out of Hospital Cardiac Arrest
Out-of-Hospital Cardiac Arrest
Primary: Number of Participants Who Survived Up To Hospital Discharge — 24; 40 Participants
N/A N=14 Open Pilot Trial of a Mind-body Program for Cardiac Arrest Survivors and Their Caregivers
Emotional Distress · Cardiac Arrest
Primary: Recruitment Feasibility Assessed by the Number of Eligible Dyads Enrolled — 7 dyads
N/A N=52 Behavioral Activation-Rehabilitation to Improve Depressive Symptoms & Physical Function After Acute Respiratory Failure
Respiratory Insufficiency · Depression · Rehabilitation
Primary: Feasibility Measure Per Participant — 0.8 proportion of intended visits
N/A N=56 Restore Resilience in Critically Ill Children
Acute Respiratory Distress Syndrome
Primary: DARE (Daytime Activity Ratio Estimate), Post Extubation — 56.7; 61.7 Percentage of total activity
N/A N=4,231 Circulation Improving Resuscitation Care (CIRC)
Cardiac Arrest · Cardiopulmonary Resuscitation
Primary: Hospital Discharge — 196; 233 participants
N/A N=48 Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest
Cardiac Arrest · Sudden Cardiac Death
Primary: Mean Systolic and Diastolic Blood Pressures — 80.38; 121.21; 61.37; 15.52 mmHg
N/A N=483 One-year Outcome After Prehospital Intubation
One-year Outcome After Prehospital Intubation
Primary: Mortality — 35 percentage of one year mortality
Phase 2 N=2 Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest
Cardiac Arrest
Primary: Intervention Compliance — 1 participants
N/A N=142 Preemptive Resuscitation for Eradication of Septic Shock
Sepsis · Severe Sepsis
Primary: Number of Participants With Worsening Organ System Dysfunction Defined by SOFA Score Increase ≥ 1 — 34; 20 Participants — p=0.064
N/A N=141 Anti-inflammatory Effect of Therapeutic Hypothermia in Out-hospital Cardiac Arrest Patients With Cardiogenic Shock
Cardiac Arrest
Primary: Survival Rate - Number of Participants Alive — 55; 20; 32; 34 Participants — p=<0.001