65,437 trials
Healthy
Primary: Mean Change in Reactive Hyperemia Index (RHI) — 0.02; -0.26 score on a scale
Breast Cancer
Primary: Acceptability of the Affect-regulated Exercise Prescription Measured Using the Treatment Acceptability and Preferences (TAP) Measure — 3.31 score on a scale
Dementia
Primary: Frequency of Agitated and Aggressive Behaviors (Staff Report) — 50.31; 48.04 score on scale — p=< 0.05
Mitochondrial Function · Physical Function
Primary: Change From Baseline in Mitochondrial Respiration in Muscle — -3.05; -4.82; -4.56 nmol O2/s/mg wwt
Visual Acuity
Primary: Proportion of Eyes With Absolute Rotation ≤ 10 Degrees — 0.9167; 0.8873 Proportion
Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma
Primary: Overall Response Rate (ORR) Assessed by the Investigator — 83.5; 74.2 percentage of participants — p=<0.0001
Nasolabial Fold Contour Deficiencies · Wrinkles
Primary: Percentage of Participants With Any Injection Site Nodule and/or Papule — 30.52; 24.84 percentage of participants
Coronavirus · Covid19
Primary: COVID-19 Symptom Duration (Phase 2) — 21.0; 18.5; 24.0; 20.5 Days
Peanut Allergy
Primary: Number of Participants With Treatment-emergent Adverse Events (TEAEs) — 15; 5; 0; 0 Participants
Healthy
Primary: Dose-normalized Area Under the Concentration-time Curve of Empagliflozin in Plasma Over the Time Interval From 0 to the Last Quantifiable Data Point (AUC0-tz) — 117.15…
Chronic Pain
Primary: Alcohol Demand: Breakpoint — -6.00; -2.07; -1.81; -1.09 dollars/drink — p=.26
Opioid-use Disorder · Opioid Dependence · Opiate Dependence
Primary: Mean Urinary Buprenorphine Levels — 861; 287 ng/ml — p=.1
Arthritis of the Knee
Primary: Cumulative Consumption of Opioids Total Daily Morphine Equivalent (TME) (mg/Day) — 23.9; 27.1 mg/day
Renal Transplant Infection
Primary: Participants Will Experience Less BK Infection Episodes Based on Viruria Results.
Pre-Eclampsia · HELLP Syndrome · Eclampsia
Primary: Duration of Severe-range Hypertension After Delivery — 38.0; 35.3 hours — p=0.3