Phase 2 N=156 Virtual Patient Behavioral Response Training for Family Caregivers
Alzheimer Disease
Primary: Revised Memory and Behavior Problems Checklist — 0.66; 0.89 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=341 A Clinical Study to Test the Effectiveness of an Investigational Drug to Treat People That Have Major Depressive Episodes When They Have Bipolar 1 Depression
Depressive Episode · Bipolar 1 Depression
Primary: Change From Baseline in Montgomery-Asberg Depression Rating Scale (MADRS) Total Score at Week 6 — -19.485; -19.324; -16.196 units on a scale — p=0.044
Phase 2 N=12 Cold Challenge With C21 in RP
Raynaud Phenomenon · Systemic Sclerosis
Primary: Area Under the Curve for Rewarming of Each Finger After Cold Challenge (AUC) as Measured by Thermography — 19558.43; 20045.96 C*sec — p==0.3801
Phase 3 N=417 Guadecitabine (SGI-110) vs Treatment Choice in Adults With MDS or CMML Previously Treated With HMAs
Myelodysplastic Syndromes · Leukemia, Myelomonocytic, Chronic
Primary: Overall Survival (OS) — 277.0; 252.0 days — p=0.6063
Phase 2 N=8 Cannabidiol Use to Reduce Cravings in Individuals With Opioid Use Disorder on Buprenorphine
Opioid-use Disorder
Primary: Change in Cue-induced Cravings and Anxiety After 3 Days of Cannabidiol Administration — 3.2; 0.4 score on a scale
N/A N=754 Interactive Parent-Targeted Text Messaging in Pediatric Clinics to Reduce Caries Among Urban Children
Caries, Dental · Health Behavior
Primary: Dental Caries Increment — 162; 161 Participants
N/A N=202 Pregnancy-Related Hypertension: Adherence to a New Type of Monitoring
Gestational Hypertension · Preeclampsia · Chronic Hypertension With Pre-Eclampsia Complicating Childbirth
Primary: Adherence to the American College of Obstetricians and Gynecologists Guideline of Postpartum Blood Pressure Check Within 10 Days Postpartum — 59; 89 Participants…
Phase 2 N=50 Phase II Study of Adenovirus/PSA Vaccine in Men With Recurrent Prostate Cancer After Local Therapy APP21
Recurrent Prostate Cancer
Primary: Number of Participants Who Develop a Strong or Modest Anti-PSA Immune Response — 12; 14; 6; 3 participants
N/A N=36 Macrophage Markers in Periodontal and Peri-implant Health and Disease
Peri-Implantitis · Periodontitis
Primary: CD80 — 7340.34; 10854.71; 6448.43; 9874.8 arbitrary density units
N/A N=10 Benefit of Assistive Listening Device for Lateralization
Hearing Loss, Sensorineural
Primary: Lateralization Hearing Ability — 71; 54 percent correct responses — p=<.05
Phase 2 N=48 Mitomycin C in Patients With Incurable p16 Positive Oropharyngeal and p16 Negative Head and Neck Squamous Cell Carcinoma (HNSCC) Resistant to Standard Therapies
Squamous Cell Carcinoma of the Head and Neck · Squamous Cell Carcinoma, Head and Neck
Primary: Tumor Response Rate (TRR) — 3; 0 Participants
Phase 4 N=2,408 Chronic Hypertension and Pregnancy (CHAP) Project
Hypertension
Primary: Composite Adverse Perinatal Outcome — 353; 427; 272; 336 Participants — p=<0.001
N/A N=2 Next Generation Sequencing-Based Stratification of Front Line Treatment of HighGrade Neuroendocrine Carcinoma
Large-Cell Neuroendocrine Carcinoma
Primary: Sequencing Rate (Feasibility)
N/A N=164 Goal2Quit + NRT Sampling
Cigarette Smoking · Smoking Cessation · Depression
Primary: 7 Day Point Prevalence Abstinence — 1; 16 Participants
Phase 3 N=90 Comparing Liposomal Bupivacaine Versus Standard Bupivacaine in Colorectal Surgery
Colorectal Surgery
Primary: VAS Score at 1 Hour at Rest — 5.0; 3.0 score on a scale — p=0.54