Phase 2 N=158 A Clinical Trial to Assess Subjects With Dry Eye Disease.
Dry Eye
Primary: Conjunctival Redness Assessed Via Digital Photography Over 90 Minutes in the Dry Eye Chamber — 0.066; 0.183 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=173 The Life After Stopping Tyrosine Kinase Inhibitors Study (The LAST Study)
Leukemia, Myeloid, Chronic
Primary: Number of Patients With Chronic Myeloid Leukemia (CML) Who Develop Molecular Recurrence After Discontinuing TKIs. — 0; 4; 12; 11 Participants
Phase 2 N=23 Effect of CT1812 Treatment on Brain Synaptic Density
Alzheimer Disease
Primary: Number of TEAEs, Related TEAEs, SAEs, and Related SAEs — 7; 8; 6; 21 Participants
Phase 4 N=176 Covid-19 Associated Coagulopathy
COVID 19 Associated Coagulopathy
Primary: Mortality — 18; 13 Participants
N/A N=83 Feasibility, Acceptability, and Barriers to Implementation of a Geriatrics Bundle in the ICU
Intensive Care Unit Syndrome
Primary: Feasibility of Bundle Delivery — 50 Participants
Phase 4 N=19 Oral vs Intravenous Diltiazem for Rapid Atrial Fibrillation/Flutter Trial
Atrial Fibrillation and Flutter
Primary: Heart Rate Control — 8; 4 Participants
Phase 2 N=87 Leronlimab (PRO 140) in Patients With Nonalcoholic Steatohepatitis
Nonalcoholic Steatohepatitis (NASH)
Primary: MRI-PDFF Change From Baseline to Week 14 — -1.25; -0.90; 0.90 Percentage of hepatic fat fraction
N/A N=34 Home-based Leg Heat Therapy
Peripheral Arterial Disease
Primary: Change in 6-min Walk Distance — -0.9; 21.3 meters
Phase 2 N=180 Study to Evaluate the Effects of Fasinumab on Peripheral Nerve Function in Patients With Pain Due to Osteoarthritis of the Hip or Knee
Osteoarthritis, Knee · Osteoarthritis, Hip
Primary: Change From Baseline in Peroneal Motor Nerve Conduction Velocity at Week 16 — -0.2; 0.2 m/sec — p=0.4192
Phase 3 N=28 Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse
Suicidal Ideation · Depression · Alcohol Abuse
Primary: Suicidal Ideation as Assessed by the Scale for Suicide Ideation (SSI) — 10.8; 12.3 score on a scale
Phase 2 N=114 Impact of Periodontal Therapy on Patients With Diabetes
Diabetes Mellitus, Type II · Periodontitis
Primary: Change in Probing Pocket Depth at the 6-month Post-SRP Completed at Baseline — -0.25; -0.18 mm — p=0.16
N/A N=60 Pan Facial Volume Restoration
Volume Loss (Soft Tissue Ptosis or Atrophy )
Primary: Mean Change From Baseline in Volume Loss Assessment — -0.8 Score on a scale
N/A N=20 EBUS-Miniforceps Biopsy Specimen Acquisition for PD-L1 Testing in Nonsmall Cell Lung Cancer
Non Small Cell Lung Cancer · NSCLC
Primary: Feasibility of Utilizing Endobronchial Ultrasound Guided Miniforceps as Assessed by the Number of Participants From Whom Adequate Amounts of Tissue to Perform PD-L1…
Phase 4 N=44 Studies of COVID-19 Patients Treated With Oral Bismuth Subsalicylate (Pepto-Bismol)
Diarrhea · COVID-19
Primary: Measure of Daily Stool Frequency for Patients With COVID Treated With Bismuth — 3 bowel movements
Phase 4 N=50 The Transversus Abdominis Plane Block: A Prospective Randomized Clinical Trial Using EXPAREL.
Postoperative Pain
Primary: Postoperative Pain Score — 4.2; 4.5 units on a scale