12,372 trials
Fecal Incontinence · Bile Acid Malabsorption
Primary: Number of Participants to Report a 50% or Greater Reduction in Weekly Fecal Incontinence (FI) Episodes — 17; 13 Participants — p=0.85
Depression, Postpartum
Primary: Change From Baseline (CFB) in the 17-item Hamilton Rating Scale for Depression (HAM-D) Total Score at Day 15 — 28.8; 28.6; -11.4; -15.6 score on a scale — p=0.0007
Acute Myocardial Infarction
Primary: Number of Participants With First CEC (Clinical Endpoint Committee) Confirmed Primary Composite Endpoint — 338; 373; 168; 191 Count of Participants — p=0.1659
Hereditary Angioedema · HAE · Prophylaxis
Primary: Safety & Tolerability — 94; 240; 58; 119 Participants
Lateral Canthal Lines
Primary: Percentage of Subjects With a ≥ 2-grade Improvement From Baseline on the Lateral Canthal Line Investigator and Subject Assessments at Maximum Smile at One Month. — 106…
Recurrent Vulvovaginal Candidiasis
Primary: Clinical Success — 85; 69; 45; 61 Participants
Prostatic Neoplasms
Primary: Overall Survival (OS) — 19.6; 19.0 Months — p=0.1677
Glabellar Lines · Lateral Canthal Lines
Primary: Percentage of Subjects Who Achieve Grade/Level 0 or 1 on the GL Investigator Scales at Maximum Frown — 769 Participants
Acute Myeloid Leukemia (AML)
Primary: Event Free Survival (EFS) — 5.98; 5.88 Months
Pain, Postoperative
Primary: Evaluation of Safety and Tolerability - Number of Subjects With an AE — 23; 26 participants
Beta-Thalassemia
Primary: Percentage of Participants Who Meet the Definition of Transfusion Independence (TI) — 91.3 Percentage of participants
Glabellar Frown Lines
Primary: Percentage of Subjects With a ≥ 2-grade Improvement From Baseline on the Glabellar Lines Investigator and Subject Assessments at Maximum Frown at One Month. — 165; 0…
Geographic Atrophy
Primary: Least Squares (LS) Mean Change From Baseline in Total Area of GA Lesions in the Study Eye at Month 12 — 1.7344; 1.7563; 1.9640 mm^2 — p=0.0615
Agitation · Schizophrenia · Schizo Affective Disorder
Primary: Change From Baseline in the Positive and Negative Syndrome Scale- Excited Component (PEC) Total Score — 17.5; 17.6; 17.6; -8.4 score on a scale — p=<0.0001
Stage I Breast Cancer AJCC v7 · Stage IA Breast Cancer AJCC v7 · Stage IB Breast Cancer AJCC v7
Primary: Complication Rate, Defined as the Percentage of Women Who Develop Grade 3 or Higher Late Adverse Event and/or Deterioration of Cosmesis From Excellent/Good to Fair/Poor…