N/A N=24 Bioavailability of SPMs in Obese Humans
Obesity Adult Onset
Primary: Mean Pro-inflammatory & Pro-resolving Metabolites — 15.6; 12.2; 6.6; 8.1 ng/mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=16 A Study Evaluating the Relative Bioavailability of Lofexidine Granules for Reconstitution Compared to LUCEMYRA (Lofexidine) Tablets and the Effect of Food on the Bioavailability of the Lofexidine Granules for Reconstitution
Normal Healthy Volunteers
Primary: Mean Maximum Plasma Concentration (Cmax) — 0.6984; 0.7275; 0.6977 ng/mL
Phase 3 N=501 A Study to Find Out if Fezolinetant Helps Reduce Moderate to Severe Hot Flashes in Women Going Through Menopause - 2
Hot Flashes
Primary: Change From Baseline in The Mean Frequency of Moderate to Severe VMS at Week 4 — -3.72; -5.53; -6.26 VMS per day — p=<0.001
N/A N=92 Trial on the Effect of Media Multi-tasking on Attention to Food Cues and Cued Overeating
Attention Concentration Difficulty · Obesity, Childhood
Primary: Amount of Time Spent Looking at Food Cues While Playing a Media Game — 9304.26; 10196.45; 8654.48; 8486.79 milliseconds
N/A N=16 MitraClip Russia Trial
Functional Mitral Regurgitation · Degenerrative Mitral Regurgitation
Primary: Number of Patients With Successful Implantation of the MitraClip NT Device — 15 Participants
N/A N=61 Patients With Chronic Knee Pain Treated With Conventional Radiofrequency of the Genicular Nerves
Chronic Knee Pain
Primary: The Number of Patients Reaching Treatment Succes at 6 Weeks Defined as Global Perceived Effect (GPE) of ≥ 50% Compared to Baseline. — 4; 15 Participants
Phase 2 N=101 LIFT Study: A Safety, Tolerability, Efficacy, and Pharmacokinetics Study of TERN-101 in Subjects With Non-Cirrhotic Non-Alcoholic Steatohepatitis (NASH)
NASH - Nonalcoholic Steatohepatitis
Primary: Number of Participants With Adverse Events for TERN-101 Versus Placebo — 10; 13; 14; 15 Participants
Phase 2 N=169 Temozolomide and Sorafenib in Treating Patients With Metastatic or Unresectable Melanoma
Melanoma (Skin)
Primary: Rate of 6 Month Progression-Free Survival — 18; 15; 4; 12 Participants
Phase 2 N=67 Diffuse Large B Cell Non-Hodgkin's Lymphoma in the Vulnerable/Frail Elderly. A Multicentric Randomized Phase II Trial
Lymphoma
Primary: Number of Participants in Complete Remission 6 Months After Randomization — 14; 9 Participants
N/A N=15 Right Ventricular Function and Exercise Capacity in Patients With Continuous-flow Left Ventricular Assist Devices
Heart Failure
Primary: Peak Oxygen Uptake — 15 ml/kg/min
Phase 2 N=45 D-serine Augmentation of Neuroplasticity
Schizophrenia · Schizo Affective Disorder
Primary: Plasticity Improvement (Change in Tone Matching Threshold) — 13.9; 5.3; 11; -0.05 log ratio
Phase 4 N=100 TREC-Lebanon: A Trial for Rapid Tranquilisation for Agitated Patients in the Emergency Setting
Psychiatric Emergency · Aggression · Agitation
Primary: Number of Participants According to the Time Taken for Aggressive Behaviour to Change to Calm and Tranquil — 18; 14; 41; 25 participants
N/A N=13 Modulating the Hippocampal and Striatal Memory Networks With rTMS
Normal Behavioral Patterns
Primary: Change From Baseline in Resting-state Functional Connectivity Between the Caudate and the Caudate Network — -0.073; -0.021; -0.029; -0.007 Fisher Z-Transformation Score
N/A N=61 Periimplant Mucosa Dynamics Around Divergent and Concave Atlantis Abutment Transition Profiles
Dental Implant, Single-Tooth · Esthetics, Dental
Primary: Peri-Implant Mucosal Zenith Distance (in Millimeters) at the Concave/Divergent Abutment Sites — 9.860; 9.770; 9.684; 9.618 millimeters
N/A N=230 An Online Health Tool About Down Syndrome: Down Syndrome Clinic to You
Down Syndrome
Primary: Number of Participants With Indicated Evaluations That Were Completed or Recommended by the PCP — 69; 79; 36; 31 participants — p=0.018