65,437 trials
Psychotic Disorders · Mood Disorders · Stress Disorders, Post-Traumatic
Primary: Reproductive Life Goal Behavioral Intentions — 3.6; 2.7; 3.3; 3.0 score on scale
Delayed Emergence From Anesthesia
Primary: Emergence Time — 9; 9 minutes
Tobacco Use Disorder
Primary: Percent of Days of Confirmed Abstinence (Out of 5 Maximum) — 46.9; 42.0 percentage of days non-smoking
Non Alcoholic Fatty Liver Disease
Primary: Change in Serum ALT (Alanine Aminotransferase) From Baseline to Week 16 — -16.3; -6.9; -10.1 U/L — p=0.5946
Multiple Sclerosis
Primary: Annualized Rate of Confirmed Relapses — 0.344; 0.283; 0.255 relapse per year — p=0.0746
Neoplasms
Primary: Number of Participants With Dose Limiting Toxicities (DLTs) in Part A1 — 0; 0; 0; 0 Participants
ADHD
Primary: Moderate to Vigorous Physical Activity (MVPA) — 53.1; 51.8 Moderate-Vigorous Minutes per day
Major Depressive Disorder
Primary: Change From Baseline Hamilton Rating Scale for Depression 24-Item Scale to Study Completion (8 Weeks) — 1.33; 11.4; 5.33; 9.25 score on a scale — p=0.292
Treatment Resistant Depression
Primary: Percent Change in the Montgomery Asberg Depression Rating Scale (MADRS) Score From Pre-treatment to 1-month — -67.07 Percentage of change in score
Sars-CoV2 · COVID-19
Primary: Time Until Cessation of Oral Shedding of SARS-CoV-2 Virus — 13; 14 days — p=0.24
Diabetic Macular Edema
Primary: Change From Baseline in Best-corrected Visual Acuity (BCVA) at Week 52 — 12.2; 11.0 Scores on a scale — p=0.099
Head and Neck Cancer
Primary: Objective Response Rate (ORR) as Determined by Blinded Independent Central Review (BIRC) - Platinum Refractory Subgroup — 13.2; 18.3 percentage of participants — p=0.2897
Hypoxic Ischaemic Encephalopathy
Primary: Lactate (Lac) / N Acetyl Aspartate (NAA) Ratio on Magnetic Resonance Spectroscopy — 0.25; 0.28 ratio
Non-invasive Lipolysis
Primary: Histology of Biopsy — 2; 2 Participants
Aging · Activity · Lifestyle
Primary: REACH Session Feedback — 5.94 score on a scale