65,437 trials
Pulmonary Disease, Chronic Obstructive
Primary: Change From Baseline in Forced Expiratory Volume in One Second (FEV1) Area Under the Curve From 0 to 3 Hours (AUC0-3h) After 4 Weeks of Treatment. — 0.250; -0.086…
Thalassemia
Primary: Percentage of Participants Achieving Erythroid Response (Week 13 to Week 24) — 77.1; 0.0 Percent of Participants
Breast Neoplasms
Primary: Progression-Free Survival (PFS) Based on Investigator's Assessment: Up to Primary Completion Date — 21.5; 13.9 Months — p=0.0012
Ambulatory IPF
Primary: Autoantibodies to Human Epidermoid (HEp)-2 Cells — 288; 177 titer
Hepatitis C
Primary: Comparison of Sustained Viral Response at 12 Weeks Post Treatment (SVR12) in the Three Treatment Groups. — 3; 5; 3; 30 Participants — p=0.67
Breast Cancer · Metastatic Breast Cancer · Recurrent Breast Cancer
Primary: Systemic Tumor Response Rates (Complete Response+Partial Response) — .25; .083; 0 proportion of tumors
Other Injury of Other Intra-abdominal Organs, Initial Encounter
Primary: Number of Participants Who Died or Had Major Abdominal Complication (MAC) — 6; 12; 6; 8 Participants
Solid Tumors · Relapsed/Refractory Sarcomas
Primary: To Establish the Dose Limiting Toxicity (DLT)
Asthma · Panic Disorder
Primary: Change in Severity of Panic Disorder as Measured by the Panic Disorder Severity Scale — 2.17; 2.40; 1.64; 1.52 score on a scale
Postoperative Pain
Primary: Change in Vaginal Pain Scores Using the Defense and Veterans Pain Rating Scale (Visual Analog Scale) Between Bupivacaine Alone Versus Exparel® Following Posterior…
CHF
Primary: Number of Participants With Treatment Related AEs and Serious Adverse Events (SAEs) — 0 Participants
Surgical Recovery
Primary: NFkB Signaling in Innate Immune Cells — 0.68; 0.69; 0.71; 0.71 NFkB (p65) arcsinh ratio
Obesity · Weight Loss · Overweight
Primary: Change in Body Weight — 10.5; 10.2; 9.9; 12.3 percent weight loss — p=.68
Endometrial Neoplasms
Primary: Progression Free Survival (PFS) Per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) Based on Blinded Independent Central Review (BICR) in Mismatch…
Breast Cancer
Primary: Correlation of Impedance Ratios Obtained Through Bioimpedance Spectroscopy (BIS) With Perometric Relative Arm Volume Change (RVC) — 0.195 correlation coefficient…