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N/A N=320 Randomized Single-blind Treatment

Project Impact: An Innovative Approach to Weight Loss Maintenance

Obesity · Weight Loss · Overweight

Enrolled (actual)
320
Serious AEs
0.0%
Results posted
Nov 2021
Primary outcome: Primary: Change in Body Weight — 10.5; 10.2; 9.9; 12.3 percent weight loss — p=.68

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Gold Standard Behavior Therapy for Weight Loss (Behavioral); Behavior Therapy for Weight Loss with Physical Activity Emphasis (Behavioral); Acceptance-based Behavior Therapy for Weight Loss with PA emphasis (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Drexel University
Primary completion
Aug 2019

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Body Weight
10.5; 10.2; 9.9; 12.3; 12.8; 11.6 .68
PRIMARY
Change in Physical Activity
64.2; 64.2; 48.6; 133.9; 143.0; 128.8 .41
SECONDARY
Cardiorespiratory Fitness
537.1; 576.6; 562.2; 503.9; 528.2; 514.1 .06
SECONDARY
Waist Circumference
42.6; 42.6; 41.8; 39.0; 39.7; 38.9 .59

Summary

The major goal of this project is to evaluate an innovative approach to obesity. This study will determine if behavioral treatment can be improved by 1) implementing a primary focus on PA following initial weight loss treatment, and 2) using a novel, acceptance-based approach to the promotion of PA.

Eligibility Criteria

Inclusion Criteria

  • Have a BMI between 27 and 45 kg/m2
  • Have the ability to engage in at least 15 minutes of moderate physical activity (e.g. brisk walking)
  • Successfully complete all steps in the enrollment process, including attendance at all pre-randomization clinic visits and providing physician clearance

Exclusion Criteria

  • Have a medical condition that prevents safe engagement in moderate-to-vigorous physical activity
  • Are lactating, pregnant, or planning to become pregnant in the next three years
  • Report recently beginning a course of or changing the dosage of prescription medications that can cause significant weight loss or weight gain
  • Are participating in or plan to participate in another weight loss program in the next three years
  • Have a primary family member or member of their household participating in the study
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02363010). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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