Phase 3 N=25 Ketamine to Prevent PPD After Cesarean
Postpartum Depression
Primary: The Prevalence of Postpartum Depression in the Study Population, as Defined as EPDS Greater Than 10 Out of 30 — 4; 2; 5 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=891 A Phase 3 Molluscum Contagiosum Efficacy and Safety Study
Molluscum Contagiosum
Primary: Complete Clearance of All Treatable MC at Week 12 — 144; 88 Participants
Phase 3 N=683 A Phase 3 Study of NI-071 in Participants With Rheumatoid Arthritis (RADIANCE)
Rheumatoid Arthritis
Primary: Stage 1: Percentage of Participants Who Achieved 20 Percent (%) American College of Rheumatology C-reactive Protein (ACR20-CRP) Response Rate at Week 22 — 56.6; 53.0…
Phase 3 N=32 Methods to Enhance AZR-MD-001 for Meibomian Gland Dysfunction (MGD)
Meibomian Gland Dysfunction
Primary: Primary Efficacy for MGD: Change From Baseline to Month 3 in Meibomian Gland Secretion Score (MGS) — 12.8; 8.8 Units on the MGS Scale
Phase 3 N=11 Efficacy/Safety of Human Plasminogen Eye Drop in Ligneous Conjunctivitis Patients
Ligneous Conjunctivitis
Primary: Percentage of Success to Prevent Pseudomembranes Relapse — 75; 81.8; 100; 100 percentage of eyes
Phase 3 N=355 A Phase 3 Efficacy & Safety of SB206 & Vehicle Gel for the Treatment of MC
Molluscum Contagiosum
Primary: Complete Clearance of All Treatable MC at Week 12 — 71; 24 Participants
Phase 3 N=156 Phase 3 Study on the Efficacy and Safety of Tanezumab in Patients With Cancer Pain Due to Bone Metastasis Who Are Taking Background Opioid Therapy
Bone Metastasis · Cancer Pain
Primary: Change From Baseline in the Daily Average Pain Intensity Numerical Rating Score (NRS) in the Index Bone Metastasis Cancer Pain Site at Week 8 — -1.25; NA; NA; -2.03…
Phase 3 N=1,317 Evaluation Of Clostridium Difficile Vaccine Lot Consistency In Healthy Adults 65 To 85 Years Of Age
Clostridium Difficile Associated Disease
Primary: Geometric Mean Concentrations (GMCs) of Clostridium Difficile Toxin A and Toxin B Specific Neutralizing Antibodies at Month 7 — 878.8; 873.0; 872.9; 5823.9…
Phase 3 N=426 Study to Evaluate the Efficacy of ALKS 3831 on Body Weight in Young Adults Who Have Been Recently Diagnosed With Schizophrenia, Schizophreniform, or Bipolar I Disorder
Schizophrenia · Schizophreniform Disorders · Bipolar I Disorder
Primary: Percent Change From Baseline in Body Weight at Week 12 — 4.91; 6.77 Percentage of change in body weight — p=.012
Phase 3 N=70 Fluoride Release,Compressive Strength and Clinical Performance of a Bioactive Restorative Material in ART
Dental Caries
Primary: the Success Rate of ACTIVA BIOACTIVE and Fuji IX Extra GIC With ART in Class I Carious Cavity of Primary Teeth — 30; 32; 28; 30 primary molars — p=0.478
Phase 3 N=11,000 Tranexamic Acid for the Prevention of Obstetrical Hemorrhage After Cesarean
Obstetrical Complications · Hemorrhage · Labor and Delivery
Primary: Number of Participants With Maternal Death or Transfusion of Packed Red Blood Cells — 201; 233 Participants — p=0.19
Phase 3 N=118 SVT-15652 Otic Solution for the Treatment of Otomycosis
Otomycosis
Primary: Therapeutical Cure (Clinical and Mycological Cure) — 48; 10 Participants
Phase 3 N=90 A Study to Assess the Effect of Cannabidiol Oil on Pain After Ureteroscopy for Kidney Stones
Urinary Stone
Primary: Maximum Pain Intensity Score — 3.6; 3.2 score on a scale — p=0.5
Phase 3 N=255 To Study Clinical Effectiveness and Safety of Olaparib Monotherapy in Metastatic Breast Cancer Patients.
HER2-ve Metastatic Breast Cancer · Germline BRCA1/2 Mutations · Somatic BRCA1/2 Mutations
Primary: Progression-free Survival (PFS) in Real-world Setting in Germline BRCA Mutated Participants — 8.18 months
Phase 3 N=174 Safety, Tolerability, and Efficacy of Zilucoplan in Subjects With Generalized Myasthenia Gravis
Myasthenia Gravis, Generalized
Primary: Change From Baseline (CFB) to Week 12 in Myasthenia Gravis-Activities of Daily Living (MG-ADL) Total Score — -2.30; -4.39 score on a scale — p=<0.001