N/A N=40 Clinical Trial Evaluating the Efficiency of Holmium Laser Settings on Urinary Stones
Stone Ureter · Stone;Renal · Surgery
Primary: Fragmentation Time — 24.5; 7.9 Minutes — p=0.012
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=35 Palbociclib / Letrozole or Fulvestrant in African American Women With HR+ HER2- Breast Cancer
Hormone Receptor Positive HER-2 Negative Breast Cancer
Primary: Number of Patients Who Complete Planned Oncologic Therapy Without the Development of a Hematological Event — 35 Participants
Phase 1 N=210 Safety, Immunogenicity, and Protective Efficacy of Two Regimens of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Natural Transmission Season in Healthy African Adults in Mali
Malaria
Primary: Number of Participants With Local and Systemic Adverse Events in Year One — 39; 27; 19; 11 Participants
Phase 2 N=221 Hydroxychloroquine in the Prevention of COVID-19 Infection in Healthcare Workers
COVID-19
Primary: Number of Participants Infected With COVID-19 or COVID-19 Like Illness During the Trial — 13; 32 Participants — p=0.0112
N/A N=46 CytoSorb Reduction of Free Hemoglobin During Cardiac Surgery
Elective Cardiac Surgery
Primary: Assessment of Serious Device Related Adverse Events — 2; 0; 16; 11 participants
N/A N=224 Breast Cancer: Feasibility of an Educational Intervention
Women's Health: Neoplasm of Breast
Primary: Feasibility of an Educational Intervention: Adherence to the Intervention — 99; 83 Participants
Phase 2 N=302 An Oral p38 Inhibitor Investigating Safety, Efficacy, And PK In Subjects With Active Rheumatoid Arthritis
Arthritis, Rheumatoid
Primary: Percentage of Participants Achieving American College of Rheumatology 20 Percent (%) (ACR 20) Response at Week 12 — 39.13; 41.89; 40.91; 40.00 percentage of participants…
Phase 2 N=47 Minocycline for Reduction of Radiation Therapy Treatment-Related Symptom Burden in Oropharynx Cancer: A Randomized Study.
Oropharynx Cancer
Primary: Combined AUC for Selected Patient Symptoms — 3.1; 3.7 score on a scale*week
Phase 3 N=275 ALTA-1L Study: A Study of Brigatinib Versus Crizotinib in Anaplastic Lymphoma Kinase Positive (ALK+) Advanced Non-small Cell Lung Cancer (NSCLC) Participants
Non-small Cell Lung Cancer · Lung Cancer · Advanced Malignancies
Primary: Progression-free Survival (PFS) — 24.016; 11.072; 16.821 months — p=<0.0001
Phase 2 N=21 Personalized Treatment Algorithms for Difficult-to-treat Asthma
Asthma in Children
Primary: Change in Composite Asthma Severity Index (CASI) — 5; 5; 5 score on a scale — p=0.52
N/A N=30 Real-time fMRI and Neurofeedback of Brain Networks Mediating Trauma Memory Recall in PTSD
Stress Disorders, Post-Traumatic
Primary: Patient Emotional Response to Volitional Engagement and Disengagement of Emotional Arousal as Measured Using Support Vector Machine Decodings When the Decoding is…
N/A N=52 Low-Frequency, High-Intensity Ultrasound for Waist Circumference Reduction
Abdominal Subcutaneous Fat
Primary: Waist Circumference Change — -2.03 Inches
N/A N=117 Intraoperative Neuromuscular Blockade and Postoperative Atelectasis
Thoracic Surgery · One-lung Ventilation
Primary: Atelectasis Area on Chest CT — 1.32; 1.41 percentage of atelectasis volume
N/A N=505 Impact of Family History and Decision Support on High-risk Cancer Screening
Colorectal Cancer
Primary: Number of Patients With Provider Referral for Risk-appropriate Colorectal Cancer Screening — 219; 232 Participants — p=0.16
N/A N=219 Changing Talk Online (CHATO) Study
Staff Attitude · Dementia
Primary: Knowledge Gain Scores for CHATO Training Participants — 63.0; 58.7; 83.8; 63.0 score on a scale — p=<.001