N/A N=55 Ultrasound Elastography in Imaging Patients With Thyroid Nodules
Malignant Thyroid Gland Neoplasm · Thyroid Gland Nodule
Primary: Stiffness of Thyroid Nodules as Measured by Elastography — 2.7; 3.8; 2.7 meters/second
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=20 Weekly Steroids in Muscular Dystrophy
Limb-girdle Muscular Dystrophy · Becker Muscular Dystrophy
Primary: Fasting Glucose — 93; 102 mg/dL
Phase 2 N=246 Alternative Schedule Study For VLA15, a Vaccine Candidate Against Lyme Borreliosis
Lyme Borreliosis
Primary: GMTs for IgG Against Each OspA Serotype — 278.5; 274.7; 21.0; 545.2 Units per milliliter (U/mL)
Phase 3 N=310 Evaluation of SPN-812 (Viloxazine Extended-release Capsule) High Dose in Children With ADHD
ADHD
Primary: Efficacy of SPN-812 Assessed by Attention-Deficit/Hyperactivity Disorder Rating Scale, 5th Edition (ADHD-RS-5) — -11.7; -17.6; -17.5 units on a scale — p=0.0038
Phase 2 N=1,359 A Study of Tanezumab in Adults With Chronic Low Back Pain
Low Back Pain
Primary: Change From Baseline in Daily Average Low Back Pain Intensity (LBPI) Score at Week 16: Baseline Observation Carried Forward (BOCF) — 6.71; 6.62; 6.57; 6.74 units on a…
Phase 3 N=4,304 A Study to Evaluate the Effect of Dapagliflozin on Renal Outcomes and Cardiovascular Mortality in Patients With Chronic Kidney Disease
Chronic Kidney Disease
Primary: Time to the First Occurrence of Any of the Components of the Composite: ≥50% Sustained Decline in eGFR or Reaching ESRD or CV Death or Renal Death. — 197; 312…
Phase 3 N=1,700 Bexagliflozin Efficacy and Safety Trial
Type 2 Diabetes Mellitus
Primary: Change in HbA1c From Baseline to Week 24 — -0.85; -0.37 percentage of glycated hemoglobin — p=<0.0001
N/A N=115 Comparative Effectiveness of Two Treatments for Veterans With PTSD
Posttraumatic Stress Disorder
Primary: Change in Clinician Administered PTSD Scale (CAPS-5) — 36.3; 34.8; 1.52; 27.8 score on a scale — p=0.28
N/A N=102 Manikin To Patient Intubation: Does It Translate?
Intubation; Difficult or Failed
Primary: Successful Intubation Encounters on Live Neonates — 1.02; 1.18 Successful Intubation Encounters
Phase 3 N=351 Safety and Efficacy of Bexagliflozin Compared to Placebo as Add-on Therapy to Metformin in Type 2 Diabetes Subjects
Type2 Diabetes Mellitus
Primary: Change From Baseline in HbA1c at Week 24 for Double-blind Group — -1.09; -0.56 percentage of HbA1c — p=< 0.0001
Phase 2 N=41 Effects of Single Agent Niraparib and Niraparib Plus Programmed Cell Death-1 (PD-1) Inhibitors in Non-Small Cell Lung Cancer Participants
Neoplasms
Primary: Stage 1: Cohort 1: Objective Response Rate (ORR) — 56.3 Percentage of participants
Phase 4 N=69 Safety, Tolerability, Pharmacokinetics and Efficacy of 180 mg Subcutaneous Risperidone From 6 mg Oral Risperidone
Schizophrenia
Primary: Steady-state Average Plasma Concentration (Cavg,ss) of Risperidone and Total Active Moiety — 5.150; 10.200; 43.730; 44.049 ng/mL
Phase 2 N=25 Inhalation Low Dose Radionuclide Therapy in Treatment COVID-19
Covid19 · Pneumonia, Viral
Primary: Count of White Blood Cells (WBC) After 99mTc-pertechnetate Aerosol Inhalation for Adverse Events Monitoring as Evaluation Safety of This Procedure in Patients With…
Phase 4 N=45 Effect on Liver Fat and Metabolic Parameters When Switching a Protease Inhibitor or Efavirenz to Raltegravir
HIV Seropositivity · Metabolic Syndrome · Fatty Liver
Primary: Change in Liver Fat — 0.3; 0.6 % hepatic fat fraction
N/A N=45 Investigation of Brain Network Dynamics in Depression
Major Depressive Disorder, Recurrent
Primary: Relative Changes in Corticolimbic Functional Connectivity as a Result of TMS — -0.11; -0.19 Fisher transformed z values