Phase 2 N=27 An Extension Study of NKTR-102 in Cancer Patients Previously Enrolled in NKTR-102 Studies
Malignant Solid Tumor
Primary: Length of Exposure to NKTR-102 — 139.0; 33.0; 126.0; 21.0 days
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=110 Clinical Accuracy of the welloStationX
Fever
Primary: Clinical Agreement Through Clinical Bias Evaluation — 0.04 degrees Farehheit
Phase 4 N=16 A Study to Evaluate Efficacy of rFVIIIFc for Immune Tolerance Induction (ITI) in Severe Hemophilia A Participants With Inhibitors Undergoing the First ITI Treatment (verITI-8 Study)
Hemophilia A With Inhibitors
Primary: Time to Tolerization With rFVIIIFc — 11.7 weeks
Phase 2 N=56 Great Auricular Nerve Block for Children Undergoing Tympanomastoid Surgery
Tympanomastoid Surgery · Cochlear Implant · Mastoidectomy
Primary: Average Observer-Rated Patient Pain Scores — 2; 1.9 units on a scale
Phase 2 N=187 A Study to Evaluate the Efficacy and Safety of Gefapixant (MK-7264) in Women With Endometriosis-Related Pain (MK-7264-034)
Endometriosis-related Pain
Primary: Change From Baseline in Average Daily Pelvic Pain Score During Treatment Cycle 2 — -2.2; -1.7 Scores on a Scale — p=0.066
N/A N=97 User Acceptability of a Device-Based Opioid Overdose Intervention
Opioid Overdose · Opioid-use Disorder · Substance Use Disorders
Primary: Community Need for a Device-based Opioid Overdose Intervention — 69; 22 Participants
Phase 4 N=548 Stop Atherosclerosis in Native Diabetics Study
Cardiovascular Disease · Hypertension · Hyperlipidemia
Primary: Changing LDL Cholesterol — 100; 70 Mg/dl
N/A N=70 Supporting and Enhancing NICU Sensory Experiences (SENSE)
Premature Birth of Newborn
Primary: Ages and Stages Questionnaire (ASQ) - Communication at 1 Year — 38.6; 48.6 score on a scale
N/A N=182 Scripps Wired for Health Monitoring Study
Diabetes · Hypertension · Cardiac Arrhythmia
Primary: Participant Perceptions of Utility of Monitoring — 13.4; 11.3 Score on a scale
Phase 2 N=49 Safety and Efficacy of PF-299804 (Dacomitinib), a Pan-HER Irreversible Inhibitor, in Patients With Recurrent Glioblastoma With EGFR Amplification or Presence of EGFRvIII Mutation. A Phase II CT.
Glioblastoma · Brain Tumor, Recurrent
Primary: Progression-free Survival (PFS) at Six Months (PFS6m) — 26; 4; 16; 1 Participants
N/A N=75 Implementing a Participatory, Multi-level Intervention to Improve Asian American Health Study
Oral Disease · Dental Caries
Primary: Number of Patients Who Agree or Strongly Agree With the Statement, "The Community Health Worker (CHW) Helped me to Improve How I Take Care of my Health" Based on a…
Phase 3 N=749 First-line Esophageal Carcinoma Study With Pembrolizumab Plus Chemo vs. Chemo (MK-3475-590/KEYNOTE-590)
Esophageal Neoplasms
Primary: Overall Survival (OS) in Participants With Esophageal Squamous Cell Carcinoma (ESCC) Whose Tumors Are Programmed Cell Death-Ligand 1 (PD-L1) Biomarker-Positive (Combined…
Phase 1 N=28 Study to Evaluate the Pharmacokinetics of Single and Multiple Doses of Apremilast in Healthy Adult Male Korean Subjects
Pharmacokinetics
Primary: Part 1: Maximum Observed Plasma Concentration (Cmax) of Apremilast — 205; 273; 373 ng/mL
Phase 2 N=160 Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes
Acute Biphenotypic Leukemia · Acute Lymphoblastic Leukemia in Remission · Acute Myeloid Leukemia in Remission
Primary: Time to Neutrophil Engraftment — 20.0; 22.0 days
Phase 3 N=276 Maxigesic IV Phase 3 Bunionectomy Study
Post Operative Pain
Primary: Summed Pain Intensity Difference (SPID)-Calculated From the Pain Intensity Scores Recorded on a 100mm Long Scale With Anchors for "no Pain" (0 mm) and "Worst Pain…