Phase 4 N=42 VO2 Max: In Vivo Model for Functional Red Cell Testing. Can RECESS be Explained?
Healthy
Primary: Percent Change From Baseline in Maximal Oxygen Uptake (VO2 Max) After Blood Cell Transfusion — 10.5; 8.5; 10.9 percent change
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=17 Pembrolizumab in Recurrent or Metastatic Medullary Thyroid Cancer
Medullary Thyroid Cancer (MTC)
Primary: Clinical Response — 0; 0 Participants
N/A N=8 Alcohol and Sex Risk Intervention for MSM Supplement
Heavy Drinking and Sexual Risk Behavior
Primary: Intervention Satisfaction Scale — 4.25 units on a scale
N/A N=90 Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder
Alcohol Use Disorder · PTSD · Cognitive Dysfunction
Primary: The Revised Hopkins Verbal Learning Test — 47.71; 44.14 units on a scale
Phase 4 N=10 Effects of Ledipasvir/Sofosbuvir on the Pharmacokinetics and Renal Safety of Tenofovir Alafenamide (TAF)
Hepatitis C · HIV Coinfection
Primary: Change From Week 12 Plasma Tenofovir Area Under the Plasma Concentration vs. Time Curve From Time 0 to 24 Hours (AUC0-24) at 24 and 28 Weeks — 3466; 743; 868 ng*h/mL
Phase 3 N=23 A Study to Evaluate the Effects of BGF and GFF on Specific Image Based Airway Volumes and Resistance in Subjects With Moderate to Severe COPD
Chronic Obstructive Pulmonary Disease (COPD)
Primary: Specific Image-based Airway Volume (siVaw) — 1.72; 1.53 Ratio to baseline — p=<0.0001
N/A N=573 ENABLE CHF-PC (Comprehensive Heartcare For Patients and Caregivers)
Heart Failure
Primary: Patient Quality of Life as Measured on the Kansas City Cardiomyopathy Questionnaire (KCCQ) Clinical Summary Score — 54.2; 51.1 score on a scale
Phase 3 N=30 Ketamine as a Treatment for Post-Traumatic Stress Disorder (PTSD)
Posttraumatic Stress Disorder (PTSD)
Primary: Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) — 22.5; 33.2 score on a scale
Phase 3 N=10 Study in Japanese Pediatric Subjects With Short Bowel Syndrome (SBS) Who Are Dependent on Parenteral Support
Short Bowel Syndrome
Primary: Absolute Change From Baseline in Parenteral Support (PS) Volume at End of Treatment (EOT) Based on Dairy Data — -11.8; -26.2 mL/kg/day
N/A N=40 Use of a Single Dose of Oral Prednisone in the Treatment of Cellulitis
Cellulitis
Primary: Visual Analog Scale(VAS) for Pain - Day 1 to 48 Hours — 79.64; 56.45; 39.71; 25.91 score on a scale
N/A N=40 Addition of Pudendal Blocks to Pelvic Floor Physical Therapy for the Treatment of Pelvic Floor Tension Myalgia
Pelvic Floor Muscle Spasm
Primary: Visual Analog Pain Score After 6 Weekly Injections — 3.33; 2.99 Visual Analog Pain Score
N/A N=44 Clinical Evaluation of the Picosure Laser for the Treatment of Unwanted Tattoos
Unwanted Tattoos
Primary: Tattoo Clearance Percentage Using a Photographic Scale — 84.7 percentage of clearance
Phase 3 N=43 A Trial Evaluating the Efficacy and Safety of HLD200 in Children With ADHD
Attention Deficit Hyperactivity Disorder
Primary: SKAMP — 11.8; 18.9 SKAMP Combined Score
N/A N=1,487 Smoker-to-Smoker (S2S) Peer Marketing and Messaging to Disseminate Tobacco Interventions
Smoking Cessation
Primary: Smoking Cessation — 89; 57; 88; 68 Participants
N/A N=294 Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty
Surgical Wound · Revision Total Knee Arthroplasty · Wounds and Injuries
Primary: Number of Participants With Surgical Site Complications (SSC) — 5; 21 Participants — p=0.0013