6,678 trials
Hypertension
Primary: Renal Oxygenation Changes After Chronic Treatment With Aliskiren or Hydrochlorothiazide — 20.5; 19.5; 19.5; 20.5 1/sec
Cervical Dystonia
Primary: Change From Baseline in Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) Severity Subscale Score Based on Blinded Rater Assessment at Week 4 After the 8th…
Breast Cancer
Primary: Number of Participants Experiencing at Least One Adverse Event — 15; 5 Participants
Post-surgical Pain · Total Knee Arthroplasty · Foot/Ankle Surgery
Primary: Pain (Average): Numeric Rating Scale for Pain — 0.5; 3.0 score on a scale
Rhinosinusitis · Chronic Eosinophilic Rhinosinusitis · Allergic Rhinosinusitis
Primary: Change in SNOT-22 (Sino-Nasal Outcome Test) — 20.7; 13.6 score on a scale
Diabetes Mellitus Type 2
Primary: Glycosylated Hemoglobin (HbA1c): — -0.75; -0.79 Percentage of HbA1c
Non-transfusion Dependent Thalassemia
Primary: Absolute Change in Liver Iron Content (LIC) at 52 Weeks From Baseline — -6.68 mg Fe/g dw
Ulcerative Colitis
Primary: Number of Participants With Corticosteroid Free Remission (SFR) — 80; 70 Participants
Renal Cell Carcinoma
Primary: Percentage of Participants Who Experienced High-Grade (Grade 3-4 and Grade 5) Immune Mediated Adverse Events (IMAEs) — 4.1; 0; 0; 0 Percentage of participants
Healthy
Primary: AUC — 3896; 3661; 3495; 3512 ng*hr/ml
Epilepsy · Cerebral Palsy · Developmental Delay
Primary: Dosage/Consumption — 0.36; 0.25 mcg/kg/min
Obesity · Labor Induction · Cesarean Delivery
Primary: Number of Participants With a Need for Cesarean Delivery — 51; 53 Participants
Irritable Bowel Syndrome With Constipation · Chronic Idiopathic Constipation
Primary: Number of Participants With Positive Treatment-Related Anti-Drug Antibodies (ADA) in Serum — 3; 1 Participants
Post-operative Pain
Primary: Opioid Requirements in Cesarean Section (C-section) Patient Population — 44; 48; 58; 57 mg
Fecal Incontinence · Neurogenic Bowel
Primary: Fecal Soiling - Number of Participants That Gained and Maintained Continence on Each Flushing Regimen — 1; 4 Participants