Phase 4 N=30 Pain Expectations in Subjects With Osteoarthritis
Osteoarthritis
Primary: Resting Pupil Diameter — 64; 72; 69; 66.9 mm — p=0.540
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=14 Influence of Testosterone Administration on Drug-Induced QT Interval Prolongation and Torsades de Pointes
Long QT Syndrome
Primary: Baseline (Pre-ibutilide) Individualized Rate-corrected QT Interval (QTF) — 393; 399; 399 ms — p=0.09
Phase 4 N=38 Live Attenuated Influenza Vaccine (LAIV) Versus Trivalent Inactivated Influenza Vaccine in Healthy Adults 18-49 Years
Influenza
Primary: Serum Antibody Responses — 11.76; 11.11; 47.03; 9.33 Titers — p=0.89
Phase 4 N=9,463 Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus
Diabetes Mellitus
Primary: Time to First Occurrence of Major Adverse Cardiovascular Events (MACE) During Cardiovascular (CV) Follow-up Time Period — 5.87; 4.57 Events per 100 person years…
Phase 4 N=26 A Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders
Urea Cycle Disorder
Primary: Percentage of Participants With Successful Transition to RAVICTI With Controlled Ammonia (i.e. No Clinical Symptoms and Ammonia < 100 μmol/L): Cohort of 2 Months to <2…
Phase 4 N=170 A Non-inferiority Trial on Pain Relief During Oocyte Retrieval
Infertility
Primary: Pain Level During Oocyte Retrieval — 0; 4; 2.5; 5 score on a scale
Phase 4 N=126 Sustaining Remission of Psychotic Depression
Psychotic Depression
Primary: Number of Subjects at Risk of Relapse During the Randomized Phase. — 13; 34 Participants
Phase 4 N=148 Clinical Trial of Efficacy and Safety of Subetta in the Combined Treatment of Patients With Type II Diabetes Mellitus
Type II Diabetes Mellitus
Primary: Changes in the Mean Value of HbA1c — -0.53; -0.01; -0.54; -0.07 percentage of HbA1c — p=0.0002
Phase 4 N=37 A Study to Compare the Amount of Nintedanib and Pirfenidone in the Blood When Nintedanib and Pirfenidone Are Given Separately or in Combination
Idiopathic Pulmonary Fibrosis
Primary: Treatment naïve, Area Under the Concentration-time Curve of the Nintedanib in Plasma Over the Time Interval 0 to the Last Quantifiable Data Point (AUC0-tz). — 150.31…
Phase 4 N=151 Clinical Trial of Efficacy and Safety of Subetta in the Combined Treatment of Patients With Type I Diabetes Mellitus
Type I Diabetes Mellitus
Primary: Changes in the Mean Value of HbA1c — -0.71; -0.49; -0.66; -0.27 percentage of HbA1c — p=0.019
Phase 4 N=27 The Effect of Intravenous Acetaminophen on Post-Operative Pain After Craniotomy
Pain
Primary: Post-operative Opioid Consumption — 228; 312 ug
Phase 4 N=447 PRET: Patients Prone to Recurrence After Endovascular Treatment
Intracranial Aneurysm · Subarachnoid Hemorrhage
Primary: Recurrence Rate of Target Aneurysm. — 102; 103 Participants
Phase 4 N=380 Azilsartan Medoxomil in the Treatment of Essential Hypertension and Type 2 Diabetes in Asia
Essential Hypertension · Type 2 Diabetes Mellitus
Primary: Percentage of Participants With Blood Pressure (BP) <140/85 mmHg (Systolic BP <140 mmHg and Diastolic BP <85 mmHg) by Clinic-Measured Sitting BP at Week 12 — 59.8; 65.9…
Phase 4 N=20 Efficacy and Safety of Aczone 7.5% Gel in the Treatment of Truncal Acne Vulgaris
Acne
Primary: Percent of Subjects Who Achieve at Least a Two Grade Improvement and a Rating of Clear or Almost Clear on the Investigator Global Assessment (IGA) Scale — 0; 3; 7…
Phase 4 N=72 LIPT - Liraglutide in Polycystic Ovary Syndrome
Polycystic Ovary Syndrome · Cardiovascular Disease
Primary: Change in Endogenous Thrombin Potential (ETP) — -56.7; -8.2 nMolar x minutes