Phase 4 N=36 Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model
Allergic Conjunctivitis
Primary: Ocular Itching at Baseline (Day 0) — 2.53; 3.08; 2.61; 2.5 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=82 A Post-Marketing Study of the Immunogenicity of Somatropin (Ribosomal Deoxyribo Nucleic Acid [rDNA] Origin) Injection (Nutropin AQ®) in Children With Growth Hormone Deficiency
Growth Hormone Deficiency
Primary: Percentage of Participants Who Develop Anti-GH Antibodies After Treatment With Nutropin AQ v1.1 — 3.7 percentage of participants
Phase 4 N=138 Enhancing the Effectiveness of Electroconvulsive Therapy in Severe Depression
Depression
Primary: Hamilton Depression Rating Scale (HDRS) — 29.5; 30.4; 12.5; 11.1 units on a scale — p=<0.05
Phase 4 N=62 Comparison of Intra-articular Dexmedetomidine and Magnesium in Postoperative Pain
Postoperative Pain · Intra-articular Injection · Dexmedetomidine
Primary: Postoperative Pain — 0; 0.04; 0.19; 0.23 score on a scale
Phase 4 N=818 Lot-to-lot Consistency Trial of Japanese Encephalitis Live Attenuated SA 14-14-2 Vaccine
Japanese Encephalitis
Primary: Number/Percentage of Subjects With Demonstrated Seroprotection — 126; 160; 154; 164 Participants — p=<0.05
Phase 4 N=159 IV Acetaminophen as an Analgesic Adjunct
Acute Pain
Primary: Change in Pain Intensity, Baseline to 60 Minutes After Medication Infused — 5.8; 5.2 units on a scale
Phase 4 N=51 A Study of Aripiprazole Lauroxil (Also Known as ARISTADA TM) in Subjects With Schizophrenia
Schizophrenia
Primary: Change From Baseline to Last Treatment Visit in Clinical Global Impressions-Severity (CGI-S) Scores — -0.2 units on a scale — p=0.078
Phase 4 N=42 Endogenous Opioid Activity and Affective State in Insulin Resistant Women
Depression · Insulin Resistance · Metabolic Syndrome
Primary: Mu-opioid Receptor Binding Potential in Left Nucleus Accumbens, Resting State
Phase 4 N=21 Wound Management for Sacral Pressure Ulcers With Necrotic Tissue
Pressure Ulcers
Primary: Percentage of Wounds Healed — 63.1; 6.1 percentage of wounds
Phase 4 N=50 Paracervical Block Versus No Paracervical Block During IUD Insertion
Analgesia · IUD Insertion
Primary: Pain Score as Assessed by a Visual Analogue Scale (VAS) — 2.4; 2.1 units on a scale — p=0.59
Phase 4 N=20 A Pharmacokinetic Analysis of Tacrolimus ER Dosing in Obese Kidney Transplant Recipients
Kidney Transplantation
Primary: Difference in Tacrolimus Exposure (AUC-0-24)) in Obese Patients Who Received an Initial TAC -ER Dose of 0.15 mg/kg Using aBW Versus IBW — 115.2; 90.0; 268.3; 269.3…
Phase 4 N=148 Subcutaneous Rehydration Compared to Intravenous Rehydration
Dehydration
Primary: Mean Total Volume of Fluid Administered at a Single Infusion Site, From the Start to the Cessation of Fluid Administration, for All Randomized Participants — 365.0…
Phase 4 N=25 Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients
Hypertension
Primary: Endothelial Cell Protein Expression p47phox From Endothelial Cell Collection — 0.47; 0.44 Ratio human to HUVEC p47Phox expression
Phase 4 N=40 Nitrous Oxide Treatment for Tinnitus
Tinnitus
Primary: Change in Tinnitus Functional Index (TFI) Score — -1.8; -2.5 score on a scale
Phase 4 N=65 Pressure Ulcer Healing With Microcyn
Pressure Ulcer · Spinal Cord Injuries
Primary: Pressure Ulcer Size (Length x Width x Depth, cm^3) at Baseline — 10.13; 21.00 cm^3