Phase 4 N=14 ABRA Abdominal Closure System in Open Abdomen Management
Open Abdomen
Primary: Primary Closure Rate — 75; 67 % of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=18 Vacuum Assisted Therapy in Emergent Contaminated Abdominal Surgeries
Gastrointestinal Injury · Complicated Diverticulitis
Primary: Rate of Surgical Site Infection — 5 Participants
N/A N=154 Negative Pressure Wound Therapy to Prevent Wound Complications Following Cesarean Section in High Risk Patients
High Risk Pregnancy · Cesarean Wound Disruption With Postnatal Complication
Primary: Wound Complication — 13; 14 Participants
N/A N=41 Damage Control for Duodenal and Combined Duodenal-Pancreatic Injuries
Injury of Duodenum · Pancreatic Injury
Primary: Duodenal-related Complications — 13; 11; 8; 19 percentage of subjects
Phase 3 N=56 Early Short-term Antibiotic Therapy in Penetrating Abdominal Trauma, 3 vs 7 Days
SURGICAL SITE INFECTION
Primary: Surgical Site Infection — 6; 3 participants — p=<0.05
N/A N=16 OxyGenesys Dissolved Oxygen Dressing; Abdominoplasty at Northwestern University
Wounds
Primary: Healing in Days. — 13.1; 12.5 days
N/A N=39 Damage Control Laparotomy
Other Injury of Other Intra-abdominal Organs, Initial Encounter
Primary: Number of Participants Who Died or Had Major Abdominal Complication (MAC) — 6; 12; 6; 8 Participants
N/A N=441 Negative Pressure Wound Therapy in Cesarean Section
Postoperative Wound Complications
Primary: Number of Participants With Wound Complication — 37; 42 Participants — p=0.54
N/A N=30 Seprafilm in Open Abdomens: a Study of Wound and Adhesion Characteristics in Trauma Damage Control Patients
Open Abdomen · Abdominal Adhesions · Trauma
Primary: Adhesion Characteristics — 1.06; 1.08; 1.13; 1.08 Scores on a scale
N/A N=283 Open Abdomen Study Comparing ABThera™ Open Abdomen Negative Pressure Therapy System and Barker's Vacuum Packing Technique
Open Abdomen
Primary: Number of Participants With Primary Fascial Closure — 139; 69 Participants — p=0.06
N/A N=539 Treatment Study of Vacuum Assisted Closure for Postsurgical Subcutaneous Abdominal Wound Healing Impairments
Wound Healing Disorder · Impaired Wound Healing · Abdominal Wound Healing Disorder
Primary: Time to Complete Wound Closure — 36.1; 39.1 Days
N/A N=120 Prophylactic Incisional Care in Obese Women at Cesarean
Wound Infections
Primary: Number of Participants With Composite Surgical Site Infection (SSI) or Other Wound Complication. — 5; 3 Participants — p=0.72
Phase 4 N=10 Use of Negative Pressure Wound Therapy in High Risk Surgical Closed Incisions
High Risk Abdominal Wounds
Primary: Number of Participants With Surgical Site Infections Within 1 Month (4 Weeks ) From Index Operation — 1 Participants
N/A N=46 Prevention of Seroma Formation and Wound Complications Using NPWT Devices
Seroma · Wound Dehiscence · Wound Infection
Primary: Post-operative Seroma Formation — 16.9; 10.1 cm^3
N/A N=24 A Prospective Case Series Evaluating Surgimend Mp® In Patients Undergoing Complex Abdominal Hernia Repair
Hernia, Ventral
Primary: The Frequency of Hernia Recurrence Diagnosed by Physical Exam or CT Scan (if Clinically Indicated) — 1 Participants
N/A N=425 A Retrospective Study Evaluating the Use of Permacol Surgical Implant in the Repair of Abdominal Wall Defects
Abdominal Wall Defects
Primary: Confirmed Hernia Recurrence — 20 participants
N/A N=81 Negative Pressure Wound Therapy in Obese Gynecologic Oncology Patients
Postoperative Complications · Obesity · Gynecologic Neoplasms
Primary: Number of Participants Who Experience Wound Complications (Wound Dehiscence or Infection) — 25; 33; 12; 9 Participants — p=0.27
N/A N=298 Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery
Surgical Site Infection
Primary: Occurrence of Superficial Surgical Site Infection — 11; 21; 107; 128 Participants
N/A N=35 Feasibility Study of The Use of FLEX HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrix in The Closure of Abdominal Wall Defects With Component Separation in Clean or Contaminated Cases
Hernia Repair With Compartment Syndrome
Primary: Hernia Recurrence — 11; 12 percentage of patients
N/A N=110 Negative Pressure Wound Therapy After Cesarean Delivery
Major Puerperal Infection, Postpartum · Wound Complications · Wound Seroma
Primary: Wound Complication Rate — 3; 1; 3; 6 participants
N/A N=101 Open Versus Robotic Retromuscular Ventral Hernia Repair
Ventral Hernia
Primary: Composite Outcome of Diagnosis of Surgical Site Occurrence or Infection, Hospital Readmission, or Hernia Recurrence — 9; 9 Participants
N/A N=21 Vacuum-Assisted Dressings (V-AD) in the Management of Open Chest Wounds
Open Chest Wounds
Primary: Duration of Negative Pressure Wound Therapy (NWPT) — 8 Days
N/A N=180 Study Evaluating Severe Surgical Site Infections (SSIs) Following Contaminated Or Dirty-infected Abdominal Surgery
Surgical Wound Infection · Postoperative Wound Infection
Primary: Percentage of Participants With Pre-surgical Morbidities — 47.8; 48.9; 26.7; 23.3 percentage of participants — p=0.881
N/A N=115 ENHANCE: A Prospective EvaluatioN of Permacol™ in tHe Repair of Complex AbdomiNal Wall CasEs
Hernia, Abdominal · Abdominal Injuries
Primary: Number of Participants With Hernia Recurrence or Undergo Reoperation for Hernia at 36 Months Post-surgery — 19; 66; 12; 73 Participants
N/A N=124 Comparison Between Wound Vacuum Dressing and Standard Closure to Reduce Rates of Surgical Site Infections
Surgical Site Infection · Pancreatic Neoplasms · Pancreatic Cancer
Primary: Rate of Surgical Site Infection — 6; 19 Participants — p=0.003
Phase 2 N=165 Randomized Clinical Trial of Skin Closure With Staples Versus Suture
Wound Infection · Wound Complication
Primary: Number of Participants With Wound Disruption or Infection (Wound Complications) Occurring Within 4-8 Weeks of the Date of the Primary Surgery. — 28; 25 Participants
N/A N=63 Vacuum Assisted Closure as a Treatment for Open Fractures
Orthopaedic Traumatic Open Fractures
Primary: Healing of Orthopaedic Trauma Open Fractures — 3.2; 4.0 use days
N/A N=122 Closed Incision Negative Pressure Therapy vs Standard of Care
Wound Complication
Primary: Prevalence of Wound Complications — 5; 11 Participants
N/A N=7 Direct Peritoneal Resuscitation Effects in the Damage Control Patient
Traumatic Injury
Primary: Number of Participants With Morbidity — 0; 0 number of participants
N/A N=104 Open Complex Ventral Incisional Hernia Repair Using Biosynthetic Material for Midline Fascial Closure Reinforcement
Ventral Incisional Hernia
Primary: Hernia Recurrence Rate — 17.3 % of subjects with recurrent hernia