Phase 4 N=2,957 High Dose Influenza Vaccine in Nursing Home - Pilot Study
Influenza
Primary: Total All-cause Hospitalizations — 197; 301 events
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=108 Use of Mobile Devices and the Internet to Streamline an Asthma Clinical Trial
Asthma
Primary: Adolescent Research Participant Assessment Score at Screening (Visit 1, Week -8) — 41.08; 42.26 Scores on a scale
Phase 4 N=77 Clinical Trial of Ingenol Mebutate Gel 0.015% & 0.05% in Actinic Keratosis
Actinic Keratosis
Primary: CC Rate of AK Lesions in the Selected Treatment Area — 49; 8; 15; 1 Participants
Phase 4 N=55 An Evaluation of the Safety and Pharmacokinetics of Tavaborole Topical Solution for the Treatment of Fungal Disease of the Toenail in Children and Adolescents
Onychomycosis · Tinea Unguium
Primary: Number of Participants With Local Tolerability Reactions by Severity — 54; 0; 1; 0 Participants
Phase 4 N=27 Allopurinol Add-on Treatment for Refractory Mania
Bipolar Disorder · Mixed Mania · Treatment-Resistant Mania
Primary: Young Mania Rating Scale (YMRS) — -12.3; -9.6 units on a scale — p=.45
Phase 4 N=17 An Open Label Study to Measure Efficacy of Fesoterodine (Toviaz) Post Surgery for Benign Prostatic Hyperplasia
Bladder Outlet Obstruction
Primary: IPSS Obstructive — 9.1; 7.5; 8.4; 7.9 units on a scale
Phase 4 N=1,500 Study Of The Blood Thinner, Apixaban, For Patients Who Have An Abnormal Heart Rhythm (Atrial Fibrillation) And Expected To Have Treatment To Put Them Back Into A Normal Heart Rhythm (Cardioversion)
Atrial Fibrillation
Primary: Number of Participants With Acute Stroke Event — 0; 6 participants — p=0.0151
Phase 4 N=463 A Study To Determine The Efficacy And Safety Of Tigecycline Compared With Imipenem/Cliastatin to Treat Complicated Intra-Abdominal Infection
Intra-abdominal Infection
Primary: Clinical Response at the Test-of-Cure (TOC) Assessment Within the Clinically Evaluable (CE) Population — 89.9; 96.6; 10.1; 3.4 percentage of participants — p=0.0008
Phase 4 N=25 A Smoking Cessation Intervention for Yale Dining Employees
Smoking Cessation
Primary: Number of Participants With a Smoking Quit Attempt in the Prior Six Weeks — 10; 1 Participants
Phase 4 N=100 Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty
Osteoarthritis · Arthroplasty
Primary: Pain Score at 3 Hours — 4.0; 2.9 units on a scale — p=0.036
Phase 4 N=36 The INDORSE Study: Inhibition of Dipeptidyl Peptidase IV: Outcomes on Renal Sodium Excretion
Type 2 Diabetes
Primary: Percent Change in Fractional Excretion of Sodium (FENA) — 41; -5.0 percentage of change — p==0.012
Phase 4 N=10 Exploring Renal Transplants Using Hepatitis C Infected Donors for HCV-negative Recipients
End-Stage Renal Disease · Hepatitis C
Primary: Number of Participants With Grade 3 or Higher Treatment-related Adverse Events as US Department of Health and Human Services Common Terminology of Adverse Events (CTCAE)…
Phase 4 N=102 Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures
Pain, Postoperative · Femur Fracture
Primary: Visual Analog Scale Pain Assessment — 5.0; 5.0; 1.6; 3.2 units on a scale
Phase 4 N=29 Anabolic and Inflammatory Responses to Short-Term Testosterone Administration in Older Men
Sarcopenia
Primary: Serum Total Testosterone Measured Before Treatment on Treatment Day 1 (Baseline Study) — 307.57; 363.43; 408.17; 318.68 ng/dL
Phase 4 N=1,950 Safety and Immunogenicity of Fluzone® Quadrivalent Vaccine Administered to Healthy Children
Influenza
Primary: Percentage of Participants With Fever (Fever Rate) Following Vaccination With Fluzone Quadrivalent Vaccine — 11.31; 12.15 percentage of participants