Phase 4 N=375 Slow Initial β-lactam Infusion With High-dose Paracetamol to Improve the Outcomes of Childhood Bacterial Meningitis
Bacterial Meningitis
Primary: Day 7 Mortality — 61; 64 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=887 Comparison of Sacubitril/Valsartan Versus Enalapril on Effect on NT-proBNP in Patients Stabilized From an Acute Heart Failure Episode.
Acute Heart Failure
Primary: N-terminal Pro-brain Natriuretic Peptide (NT-proBNP) Values and Time-averaged Change From Baseline — 0.7466; 0.5333 pg/ml — p=<.0001
N/A N=137 A Clinical Evaluation of the Eclipse™ System, a Vaginal Bowel Control (VBC) Therapy for Fecal Incontinence in Women
Fecal Incontinence
Primary: Count of Treatment Responders in the Intent to Treat (ITT) Cohort — 53 Participants
Phase 2 N=60 The Efficacy and Safety Study of Tung's Acupuncture for Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome
Primary: Change in LH/FSH Ratio From Baseline to the End of Treatment — -0.66; -0.96 ratio
Phase 4 N=100 Clinical Investigation of the Bi Flex M Multifocal IOL
Cataract
Primary: Long Term Monocular Visual Acuity (VA) — 0.192; 0.205; 0.614; 0.319 LogMAR
Phase 2 N=30 Efficacy, Safety, and Tolerability of HTS-519 Insert in Patients With Toenail Fungus of the Big Toenail
Onychomycosis
Primary: Treatment Related Adverse Events — 22; 8 Participants
Phase 1 N=204 A Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Autoinjector (PFS+AI) in Healthy Participants
Healthy Volunteers
Primary: AUClast: Area Under the Serum Concentration-time Curve From Time 0 to the Time of the Last Quantifiable Concentration for Vedolizumab SC — 402.8; 452.3 microgram*day per…
Phase 1 N=19 A Phase I Imaging and Pharmacodynamic Trial of CS-1008 in Patients With Metastatic Colorectal Cancer
Colorectal Neoplasms
Primary: Number of Subjects With Tumor Uptake of 111^In-CS-1008 in Target Lesions Based on Gamma Camera Imaging Following the Day 1 and Day 36 Infusions — 0; 3; 3; 3 participants
Phase 4 N=6,998 STudy to vAlidate telemetRic ECG Systems for firsT Dose Administration of Fingolimod (START)
Multiple Sclerosis
Primary: Participants With 2nd or 3rd Degree Atrioventricular (AV) Block — 120; 117; 0; 43 Participants
Phase 2 N=52 Long-Term Assessment of Remyelinating Therapy
Acute Optic Neuritis
Primary: FF-VEP Latency of the Affected Eye as Compared to the Baseline of the Fellow Eye at 2 Years (+ up to 12 Months) After the Last Study Visit Assessment (Week 32) in RENEW…
Phase 3 N=602 Edoxaban Treatment Versus Vitamin K Antagonist (VKA) in Patients With Atrial Fibrillation (AF) Undergoing Catheter Ablation
Atrial Fibrillation
Primary: Number of Participants Who Experienced the Composite of All-cause Death, Stroke (VARC-2), and Major Bleeding (ISTH) in the Edoxaban Group Compared With Vitamin K…
Phase 4 N=379 A Randomized, Multicenter, Open-label, Parallel-group, 12-week Study to Assess the Efficacy and Safety of Switching From Tiotropium to QVA149 (Indacaterol Maleate/Glycopyrronium Bromide) in Symptomatic Mild to Moderate COPD Patients
COPD
Primary: Trough Forced Expiratory Volume In One Second (FEV1) After 12 Weeks of Treatment — 0.0668; 0.0090 Liters — p=0.0129
N/A N=25 Detachable String Magnetically Controlled Capsule Endoscopy for Completely Viewing of Esophagus and Stomach
Outpatients
Primary: Number of Participants With Successful Separation of Capsule and String, and Complete Viewing of Esophagus and Stomach — 25 Participants
N/A N=80 A Trial to Evaluate the Efficacy and Safety of EFLA400 Korea Red Ginseng Extract on Sexual Function in Men With Erectile Dysfunction
Healthy Subjects(Only Men)
Primary: Changes in EF(Erectile Function) Domain — 11.53; 12.89; 14.56; 16.46 Scores on a scale
Phase 1 N=70 A Study of Nasal Glucagon in Participants With Type 1 Diabetes Mellitus
Hypoglycemia · Diabetes Mellitus, Type 1
Primary: Percentage of Participants Achieving Treatment Success During Controlled Insulin-Induced Hypoglycemia — 66; 66 Participants