Early Phase 1 N=92 Aspirin Resistance in Coronary Artery Disease
Coronary Artery Disease
Primary: Change in Serum Thromboxane B2 — 5.02; 2.78 ng/mL — p=0.005
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Early Phase 1 N=35 Dose-dependent Anti-inflammatory Effects of Vitamin D in a Human Gingivitis Model
Gingivitis
Primary: Proportion of Sites That Bleed on Probing
Early Phase 1 N=15 Vismodegib in Treating Patients With Basal Cell Carcinoma (BCC)
Basal Cell Carcinoma of the Skin · Recurrent Skin Cancer
Primary: Percent Change in Surgical Defect Area After the Treatment Period Using Calipers and Photographs Was Calculated — -26.8 percentage size change from baseline
Early Phase 1 N=2 Targeting a Genetic Mutation in Glycine Metabolism With D-cycloserine
Schizophrenia · Bipolar Disorder
Primary: Positive and Negative Symptom Scores — 14.5; 11; 14.5; 14 units on a scale
Early Phase 1 N=17 A Pilot Study of Trans Arterial Chemoembolization (TACE), Followed by Stereotactic Radiation Therapy (SBRT) for Patients With Hepatocellular Carcinoma
Hepatocellular Carcinoma (HCC)
Primary: Safety of a Combination Therapy — 0 participants
Early Phase 1 N=146 Feasibility of Delivering a Quitline Based Smoking Cessation Intervention in Cancer Patients
Lung Cancer · Tobacco Use Disorder · Breast Cancer
Primary: Feasibility of a Smoking Cessation Intervention Among Cancer Patients — 55; 33 Participants
Early Phase 1 N=26 Intranasal Oxytocin Administration and the Neural Correlates of Social and Non-Social Visual Perception
Social Perception
Primary: Amplitude Social — -3.72; -3.55; -3.28; -3.30 microvolts — p=.003
Early Phase 1 N=14 DSC-MRI With Ferumoxytol and DCE-MRI With Gadolinium in Imaging Vascular Properties in Younger Patients With Brain Tumors
Childhood Brain Neoplasm · Recurrent Childhood Brain Neoplasm
Primary: Vascular Properties of Pediatric Brain Tumors Using Dynamic Susceptibility-weighted Contrast Enhanced MRI (DSC-MRI) After Administration of Ferumoxytol — .93 mL/g
Early Phase 1 N=17 The Effect of Eszopiclone on the Arousal Threshold in Sleep Apnea Syndrome
Obstructive Sleep Apnea
Primary: Apnea Hypopnea Index — 24; 31 events per hour of sleep
Early Phase 1 N=6 Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas
Neurofibromatosis · NF1 · Neurofibromas
Primary: Disease Response — 0; 0; 2; 1 Participants
Early Phase 1 N=8 CCRC: A Project of the Treatment of HIV Enteropathy With ImmunoLin® Supplements
HIV
Primary: Number of Bowel Movements Per Day — 5.8; 2 bowel movements/day — p=0.008
Early Phase 1 N=10 Phase 0/1 Biomarker and Pharmacodynamic Study of Roflumilast in Patients With Advanced B-Cell Hematologic Malignancies (CTRC# 13-0013)
Advanced B-cell Lymphoid Malignancies
Primary: Total Number of Adverse Events. — 2 Adverse events
Early Phase 1 N=12 TOPIC Trial for COPD
Chronic Obstructive Pulmonary Disease
Primary: Change in COPD as Measured by the Sweat Analysis in Each Group — -8.0; 2.0 mmol/L
Early Phase 1 N=10 Investigation of the Glycemic Index of Ethiopian Honey
Hyperglycemia, Postprandial
Primary: Examine Effect of Monofloral Honey Types on Glycemic Index of Health Human Subjects — 54.73; 62.82; 60.31; 59.54 Index — p=<0.01
Early Phase 1 N=30 Long Term Effect of Buspirone on Esophageal Function and Esophageal Symptoms in Patients With Systematic Sclerosis (SSc)
Systemic Sclerosis
Primary: Changes From Baseline in Manometric Parameters: i) Amplitude of Contractions at the Distal Part of the Esophagus and ii) Resting and Residual (Lower Esophageal Pressure)…