6,678 trials
Liver Transplant
Primary: Infection Rates — 27; 26; 11; 7 Participants — p=0.841
Depression
Primary: Changes in Mu-opioid Binding Potential During PET — 0.12 Binding potential ratio — p=<0.001
Coronary Artery Disease
Primary: P2Y12 Reaction Unit (PRU) — 284.1; 284.1; 39.1; 37.5 PRU
Schizophrenia · Cigarette Smoking
Primary: Cotinine Level — 257.9; 258.6; 176.0; 252.1 cotinine ng/ml
Influenza, Human
Primary: Anti Influenza Hemagglutination Inhibition (HAI) Antibody Geometric Mean Titers (GMT) — 3.80; 3.77; 5.72; 5.70 Titers
Age-related Macular Degeneration
Primary: Change From Baseline in Plasma Vascular Endothelial Growth Factor (VEGF) Concentration After First Injection at Visit 5 (Day 8 +/- 1 Day) — 5.720; -25.833 pg/mL
Obesity
Primary: Change in PAI-1 Level — 39.5; 31.6; 28.6; 37.9 ng/ml — p=0.0005
Blood Component Transfusion
Primary: Number of Participants With Changes in the Production of Antibody to HLA Antigens — 2; 6; 2; 5 Participants
Smoking Cessation
Primary: Percentage of Participants With 30-day Abstinence — 18.0; 23.4; 22.1; 18.7 percentage of participants
Varicose Veins · Telangiectasis
Primary: Change From Baseline in Extent of Telangiectasias — 57.24; 76.08 percent of change negative values
Hypertension · Left Ventricular Diastolic Dysfunction
Primary: Improvement in Exercise Tolerance — 9; 8 Participants
Chronic Obstructive Pulmonary Disease
Primary: Change in Patient-Reported Breathing Difficulty - Using Modified Borg Dyspnea Scale — -1.4; -1.0 units on a scale — p=0.320
Snake Bites
Primary: Patient Specific Functional Scale Score — 8.62; 7.45 units on a scale
Major Depressive Disorder
Primary: Change in Hamilton Rating Scale for Depression — 8.4 units on a scale
Hyperkalemia
Primary: Percentage of Subjects With Serum Potassium in the Target Range (3.8 - 5.0 mEq/L) at Either Week 3 or Week 4 — 82.5; 87.3 percentage of participants