Phase 2 N=70 Pomalidomide for Myelofibrosis Patients
Polycythemia Vera · Thrombocythemia
Primary: Number of Participants With Best Overall Response — 0; 3; 6 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=628 PCORI-1306-02918 Evaluation of Parent-based Programs to Support Children After Traumatic Injury
Psychological Trauma · Depression · Coping
Primary: Post-traumatic Stress Symptoms (Child Post-traumatic Stress Disorder (PTSD) Scale) Through the First and Last Survey Administered Post-Baseline — 10.64; 8.53; 9.87; 8.17…
N/A N=329 Effectiveness of Peer-Delivered Trauma-Specific Treatment
Post-Traumatic Stress Disorder · Substance Use Disorders
Primary: Change in Post-traumatic Stress Disorder Symptoms — 47.2; 48.2; 43.9; 44.7 Score on a Scale — p=0.01
N/A N=81 Usefulness and Safeness Of Intra-Gastric Balloon Before Bariatric Surgery In Morbid Obesity
Morbid Obesity
Primary: Postsurgical Morbidity on Both Arms of the Study — 10; 8; 8; 4 Participants — p=0.689
N/A N=64 Study of Aortic Root Reimplantation Procedure
Ascending Aortic Aneurism · Aortic Valve Insufficiency
Primary: Freedom From Aortic Insufficiency More Than 2+ (Percentage, Kaplan-Meier) — 88.2; 87.7 percentage of participants
N/A N=62 Evaluation of Pain Associated With the Removal of Wound Dressing During Care of Venous Leg Ulcer. Comparison of the Efficacy and Safety of Two Dressings Urgotul and TulleGras
Venous Leg Ulcer
Primary: Pain Intensity at Removal of the Primary Dressing, Evaluated by the Subject Just After Removal — 11.9; 11.7 units on a scale: 0-100 mm
Phase 3 N=142 Radial Artery Versus Saphenous Vein Patency (RSVP) Study
Coronary Arteriosclerosis
Primary: Patency Rates — 38; 58; 6; 1 Participants
N/A N=995 Neonatal Outcome by Reason for Delivery
Preterm Delivery
Primary: Composite Perinatal Morbidity — 277; 203; 221; 45 participants
Phase 3 N=635 Ibuprofen/Caffeine Lower Back or Neck Pain Study
Back Pain · Neck Pain
Primary: Change in Pain on Movement (POM) With Regard to the Worst Procedure (WP) Between Baseline and Day 2 (Morning, 2 Hours After Drug Intake) — 1.712; 1.998; 1.869 Unit on…
Phase 3 N=243 The Long-term Antibody Persistence of MenACWY-TT Vaccine (PF-06866681) Versus Meningitec(Registered) or Mencevax(Registered) ACWY in Healthy Adolescents and Adults and a Booster Dose of MenACWY-TT Administered 10 Years Post Primary Vaccination
Infections, Meningococcal
Primary: Persistence Phase: Percentage of Participants With Serum Bactericidal Assay Using Rabbit Complement (rSBA) Titers >=1:8 and >=1:128 For Each of the 4 Serogroups After 6…
Phase 4 N=322 Visual Outcome in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) Treated With Either Ranibizumab as Monotherapy or Combined With Verteporfin Photodynamic Therapy (vPDT)
Age-related Macular Degeneration · Polypoidal Choroidal Vasculopathy
Primary: Mean Change From Baseline in Best Corrected Visual Acuity (BCVA) at Month 12 - Study Eye — 8.3; 5.1 Letters — p=<0.001
Phase 1 N=12 A Phase 1 Food Effect Study of Azilsartan (TAK-536) Pediatric Formulation
Healthy Volunteers
Primary: Cmax: Maximum Observed Plasma Concentration for TAK-536 — 652.6; 609.4 nanogram per milliliter (ng/mL)
N/A N=46 Evaluation of the Immune Response to Clostridium Difficile in Adults With Clostridium Difficile Infection (CDI)
Infections, Clostridium Difficile
Primary: Serum Anti-toxin A and Anti-toxin B Antibody Concentrations at Day 14 — 2083.3; 3189.4; 32096.4 EU/mL — p=0.5746
Phase 3 N=865 Glutamate for Metabolic Intervention in Coronary Surgery
Coronary Artery Bypass · Myocardial Ischemia · Myocardial Infarction
Primary: Number of Participants With Perioperative Myocardial Infarction, Postoperative Heart Failure or Postoperative Mortality — 31; 25 Participants
N/A N=64 Effect of Inflammation on Pharmacokinetics of Posaconazole
Mycoses
Primary: C Reactive Protein Levels in mg/L (CRP) on Posaconazole Concentrations in mg/L — 1.8; 23.5 mg/L — p=0.77