65,437 trials
Diphtheria-Tetanus-acellular Pertussis Vaccines
Primary: Antibody Concentrations Against Pertussis Toxoid Antigen (Anti-PT), Filamentous Haemagglutinin Antigen (Anti-FHA) and Pertactin Antigen (Anti-PRN) in Cord Blood Samples…
Severe Familial Hypercholesterolemia
Primary: Number of Participants With Adverse Events — 94; 174; 76; 143 Participants
Influenza, Human
Primary: Number of Participants With Immediate Adverse Events — 0; 0 participants
Asthma
Primary: Change From Baseline in Eosinophils Cells Count in the Bronchial Submucosa at Week 12 — 5.80; -6.04 cells/mm^2 — p=0.8400
Schizophrenia · Schizoaffective Disorder · Schizophreniform Disorder
Primary: Change in Weight — -2.0021; -1.5490 kg. (killograms)
Obesity · Colorectal Carcinoma
Primary: Change in Weight — 9.2; 6.6 lbs
Chronic Hepatitis C
Primary: Percentage of Participants Achieving Sustained Virological Response 12 Weeks Post-treatment (SVR12) — 98.1 percentage of participants
Relapsing Remitting Multiple Sclerosis
Primary: Annual Relapse Rate (ARR) — 0.290; 0.354 Relapses per year — p=0.3118
Labor and Delivery
Primary: Composite of Severe Neonatal Morbidity and Perinatal Mortality — 164; 132 Participants — p=0.049
Advanced and Metastatic Silent Neuro-Endocrine Tumors · Carcinoma · Neuroendocrine
Primary: Percentage of Participants' Best Overall Response Rate at 12 Months - Per Protocol Set (PP) — 0.0; 0.0; 56.7; 43.3 percentage of participants
Chronic Myelomonocytic Leukemia · Previously Treated Myelodysplastic Syndrome · Recurrent Adult Acute Lymphoblastic Leukemia
Primary: The MTD of Radiation Delivered Via 90Y-DOTA-BC8 When Combined With FLU and 2 Gy TBI as a Preparative Regimen for Patients Aged ≥ 18 With Advanced AML, ALL, and High-risk…
Sickle Cell Disease
Primary: Average Percent Hemoglobin (HbA) Decrement Per Day — 0.629; 0.659 %HbA per day — p=0.95
Acute Lymphoblastic Leukemia
Primary: The Primary End-point is the Number of Patients in CR After Induction Therapy. — 9 Participants
Infections, Rotavirus
Primary: Incidence Rates of Intussusceptions (IS) Among the HRV Cohort and Comparator Cohorts — 0.021; 0.022; 0.021; 0.028 Incidences/Person-Month
Metastatic Seminoma
Primary: 2 - Year Progression Free Survival — 46 Participants