65,437 trials
Hypertension
Primary: Changes in Clinic Blood Pressure in the Sitting Position — -20.1; -18.1; -10.4; -9.3 mmHg
Systemic Lupus Erythematosus
Primary: Frequency of Participants With Adverse Events — 21; 33 Participants
Oral Leukoplakia · Oral Lichen Planus · Premalignant Lesion
Primary: Number and Percentage of Lesions That Were Stained Positive — 29; 28 lesions — p=0.005
Morbid Obesity
Primary: Percent Weight Change — 11.5 percentage of excess weight loss
Stroke · Cerebral Vascular Accident
Primary: Ankle Dorsiflexion Angle. Change From Baseline in Ankle Dorsiflexion Angle During the Swing Phase of Gait — 3.85; .18; -4.15; -1.60 degrees — p=.05
Leukemia · Lymphoma
Primary: Engraftment — 15; 15 days
Prostate Cancer
Primary: Progression-Free Survival (PFS) — 2.3; 2.4 months — p=0.2201
Opioid Use Disorder · Opioid-related Disorders
Primary: Participants With Treatment-Emergent Adverse Events (TEAE) During the Treatment Period — 71; 14; 5; 0 Participants
Pregnancy Induced Hypertension · Superimposed Preeclampsia · Hypertension
Primary: Number of Participants With Adverse Events — 2; 0 participants
Energy Deficiency Due to Short-term Fasting
Primary: Leptin Pharmacokinetic Parameters - TIME(T1/2) DAY 3 / TMAX DAY 3 72-hour Fasting Day 3 Leptin Dose 0.01 mg/kg — 1.93; 2.75; 2.99; 2.00 HR
Normal Subjects Who Agree to Participate in Taste Testing
Primary: Overall Liking of Apple Crisp — 7.31; 6.83; 7.22 score on likert rating scale
Spinal Cord Injuries
Primary: SCI-QoL Independence — 49.9 units on a scale
Keratoconus
Primary: Number of Participants With an Observable Difference Between Virtual Versus Actual Fluorescein Patterns — 0 participants
Pregnancy
Primary: The Ability of the Volunteer to Use the New Clearblue Advanced Fertility Monitoring a Home Setting — 89.7 percentage of participants
Breast Cancer
Primary: Complete Pathological Response (pCR) Rate in Breast and Axilla According to the Miller&Payne Criteria (G5-A and G5-D). — 23.5; 47.9 percentage of participants with pCR