N/A N=87 Performance Comparison Between Comfilcon A and Senofilcon C Lenses
Myopia
Primary: Overall Lens Fit Acceptance — 3.6; 3.5; 3.5; 3.5 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=197 PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - Nested Registry 3/Valve-in-Valve
Aortic Stenosis · Cardiomyopathy, Hypertrophic
Primary: Number of Participants With All-Cause Mortality, All Stroke, Moderate or Severe Obstruction, or Moderate or Severe Paravalvular Leak (Composite) — 28 Participants
Phase 2 N=110 Safety and Tolerability Study of Voreloxin and Cytarabine Combination in Acute Myeloid Leukemia in Humans
Acute Myeloid Leukemia
Primary: Incidence of Dose-Limiting Toxicity (DLT) to Determine Maximum Tolerated Dose in Schedule A and Schedule B of Dose Escalation Phase (Group 1 and Group 2) — 0; 0; 0; 0…
Phase 4 N=30 Countermeasures to Reduce Sensorimotor Impairment and Space Motion Sickness Resulting From Altered Gravity Levels
Vestibular
Primary: Percent Change in Roll Tilt Perception After Exposure to Hypogravity — 27.0 percentage change
Phase 2 N=67 Phase II Copanlisib in Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL)
Diffuse, Large B-Cell, Lymphoma
Primary: Objective Response Rate (ORR) in Total Population Based on Investigator Assessment — 19.4; 25.0 Percentage of participants
N/A N=87 CBT for Adherence and Depression in Diabetes
Diabetes Mellitus · Depression
Primary: Glucose Monitoring Adherence at Acute Outcome — 49.63; 79.79 percentage of glucose monitoring goal — p=<.0001
N/A N=26 Investigating Transcranial Ultrasound as a Potential Intervention for Depression
Depression · Anxiety Disorders
Primary: Depressive Symptoms Assessed With the Beck Depression Inventory-II — -4.42; -.650 units on a scale
Phase 3 N=120 Traditional Clomiphene Citrate Administration vs. Stair-step Approach
Ovulatory Dysfunction · Anovulation · Ovulation Induction
Primary: Time to Ovulation With Each Protocol — 31.1; 21.5 days
Phase 3 N=12,546 A Study to Assess the Efficacy and Safety of Enteric-Coated Acetylsalicylic Acid in Patients at Moderate Risk of Cardiovascular Disease
Moderate Risk of CVD
Primary: Time to the First Occurrence of the Composite Outcome of MI (Myocardial Infarction), Stroke, Cardiovascular Death, UA (Unstable Angina) or TIA (Transient Ischemic…
Phase 4 N=180 Safety and Immunogenicity of Fluzone® Quadrivalent and Fluzone® High-Dose, Influenza Vaccines, 2016-2017 Formulations
Influenza
Primary: Number of Participants Reporting Solicited Injection Site Reactions (Pain, Erythema, and Swelling) and Systemic Reactions (Fever, Headache, Malaise, Myalgia): Group 1 (3…
Phase 2 N=224 Safety of a Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine in Healthy Subjects in Vietnam
Meningitis · Meningococcal Meningitis · Meningococcal Infections
Primary: Number of Participants Reporting Solicited Injection-Site Reactions Following Vaccination: Menactra® Vaccine (9 to 23 Months) — 15; 0; 15; 0 Participants
Phase 2 N=226 Open-label, Uncontrolled Phase II Trial of Intravenous PI3K Inhibitor BAY80-6946 in Patients With Relapsed, Indolent or Aggressive Non-Hodgkin's Lymphomas
Lymphoma, Non-Hodgkin
Primary: Objective Response Rate (ORR) Based on Independent Review-Part A — 43.75; 27.08 percentage of participants — p=0.0001
N/A N=32 Heated Humidified Oxygen Compared to Dry Oxygen Therapy in Children With Bronchiolitis
Bronchiolitis · Hypoxemia
Primary: Change in Respiratory Distress Assessment Instrument (RDAI) From Baseline. — 4.69; 2.69; 4.27; 3 units on a scale
N/A N=2 Irreversible Electroporation Ablation for Colorectal Metastases to the Lung
Colorectal Metastases to the Lung
Primary: The Frequency of Adverse Events
N/A N=108 Behavioral Differences in Effortful Control
Healthy
Primary: Reaction Time on the Multi-Source Interference Task — 300; 330; 310; 280 milliseconds — p=0.159