Phase 3 N=224 PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge
Social Anxiety Disorder
Primary: Subjective Units of Distress Scale (SUDS) Score — 77.7; 78.2; 62.3; 61.3 score on a scale — p=.5063
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=1,801 Inactivated Split Virus Seasonal Influenza Vaccine (Vero Cell-Derived)
Influenza
Primary: Hemagglutination Inhibition Antibody (HIA) Titer for Each of the Three Antigens Contained in the Vaccine — 269.7; 337.3; 288.5; 297.1 Titers
Phase 3 N=53 Efficacy and Safety of Tideglusib in Congenital Myotonic Dystrophy
Congenital Myotonic Dystrophy
Primary: Change in Clinician-Completed Congenital DM1 Rating Scale (CDM1-RS) — -1.65; -3.40 score on a scale — p=0.0514
Phase 3 N=112 A Study of SEL-212 in Patients With Gout Refractory to Conventional Therapy
Chronic Gout
Primary: Proportion of Participants Who Achieved and Maintained Reduction in Serum Uric Acid (sUA) < 6 Milligrams Per Deciliter (mg/dL) for At Least 80% of The Time During…
Phase 3 N=581 Study to Evaluate the Efficacy & Safety of the INTERCEPT Blood System for RBCs in Complex Cardiac Surgery Patients
Anemia
Primary: Percentage of Patients Who Have Received at Least One Study Transfusion With a Diagnosis of Renal Impairment Defined as: — 46; 45 Participants
Phase 3 N=178 A Phase III Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus.
Uremic Pruritus
Primary: Change From Baseline in the Mean NRS Score at Week 4 — -2.06; -1.09 points — p=<0.001
Phase 3 N=35 Genotype-tailored Treatment of Symptomatic Acid-Reflux in Children With Uncontrolled Asthma
Asthma · Gastroesophageal Reflux
Primary: Change in Asthma Control Questionnaire (ACQ) From Screening Through Week 26 — -0.5; -0.6 score on a scale — p=0.8716
Phase 3 N=195 Effects of Triptorelin Pamoate 6-month When Given to Adult Chinese Participants With Advanced Cancer in the Prostate
Advanced Prostate Cancer · Metastatic Prostate Cancer · Locally Advanced Prostate Cancer
Primary: Percentage of Participants Who Achieved Castrate Levels of Serum Testosterone on Day 29 — 99.5 percentage of participants
Phase 3 N=264 Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps (ANCHOR-2)
Nasal Polyps
Primary: Change From Baseline in Total Endoscopic Nasal Polyps (NP) Score at Week 52 (Centrally Read) — -0.5; 0.1 Scores on scale — p=0.004
Phase 3 N=230 Administration of Ketamine to Prevent the Post-operative Pain
Postoperative Pain · Breast Cancer
Primary: Morphine Consumption (First 48 Post-operative Hours) — 79; 77 Participants
Phase 3 N=50 Croup Dosing Study
Croup
Primary: Return Visits or Readmissions to the Hospital — 0; 2 participants
Phase 3 N=370 A 12-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Osteoarthritis Pain of the Knee
Osteoarthritis Pain of the Knee
Primary: Change From Baseline to Week 12 in WOMAC Pain Score (Intent-to-treat Set) — -4.6; -5.4 score on a scale
Phase 3 N=598 Safety and Efficacy of TRx0237 in Subjects With Alzheimer's Disease Followed by Open-Label Treatment
Alzheimer Disease
Primary: Change From Baseline on Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-cog11) (16 mg/Day vs Control) — 1.71; 1.34 score on a scale
Phase 3 N=576 A Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose Compared With CHF 718 pMDI 800µg Total Daily Dose in Adults With Asthma on Medium or High-Dose Inhaled Corticosteroid
Asthma
Primary: 1_Change From Baseline in FEV1 AUC0-12h Normalised by Time at Week 12 — 0.279; 0.174 liter — p=<0.001
Phase 3 N=60 Safety and Pharmacokinetics of Dolutegravir in Pregnant HIV Mothers and Their Neonates: A Pilot Study
HIV · Pregnancy
Primary: AUC0-24 of DTG in Pregnant Women in Third Trimester and 2 Weeks Postpartum — 35322; 40127 ng*h/mL