Phase 4 N=1,077 Self-Administered Nasal Influenza Feasibility Study
Influenza
Primary: Post-vaccination Geometric Mean Titer (GMT) Ratios Between HCWA and SA Subjects — 45.8; 48.7; 45.5; 46.4 titer ratio — p=0.43
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=20 Memantine for Treatment of Cognitive Impairment in Patients With Parkinson's Disease and Dementia
Parkinson's Disease · Cognitive Impairment · Dementia
Primary: Change in Dementia Rating Scale (DRS) Memory Subscore — 1.6; -1.4 units on a scale
Phase 2 N=1,803 Evaluation of a Vaccine for Reducing Ear and Lung Infections in Children
Infections, Streptococcal
Primary: Time to Occurrence of Any Acute Otitis Media (AOM) Diagnosed and Verified Against American Academic of Pediatrics (AAP) Criteria — 0.425; 0.442 Episodes per person-year…
Phase 4 N=32 Glutamatergic and GABAergic Mediators of Antidepressant Response in Major Depression
MDD · Citalopram · Major Depressive Disorder
Primary: Mean Difference From Baseline to Day 3 in Glutamine/Glutamate (Gln/Glu) Ratio Within Depressed Group — 0.015 arbitrary units
Phase 4 N=101 Use of Dabigatran Etexilate to Prevent Stroke and Thromboembolism
Atrial Fibrillation · Atrial Flutter
Primary: Frequency of Major Bleeding Complications in Patients Administered Dabigatran Following RF Ablation. — 1 number of events
Phase 4 N=25 A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis
Pulmonary Arterial Hypertension · Systemic Sclerosis · Scleroderma Spectrum of Diseases
Primary: Right Ventricular (RV) Mass — 32.5; 28.0 grams
N/A N=100 Fluoroscopy-guided Versus Traditional Placement of Epidural Catheters
Pain, Postoperative · Pain, Chronic
Primary: Intravenous Pain Medication — 63; 66 milligrams
Phase 2 N=83 4 Week Switch Study in Hemodialysis-dependent Subjects With Anemia Associated With Chronic Kidney Disease
Anaemia
Primary: Modeled Hemoglobin (Hgb) Change From Baseline (Pre-dose on Day 1) at 4 Weeks of Treatment — -1.130; -1.070; 0.212; -0.273 Grams per deciliter (g/dL) — p=0.0135
N/A N=76 Dexamethasone in Reducing Oral Pain and Dry Mouth After Surgery in Patients With Oropharyngeal Cancer
Dysphagia · Pain · Stage I Oropharyngeal Squamous Cell Carcinoma
Primary: Pain Visual Analogue Scale (VAS) Score Measured at 10-point Scale — 7.4; 6.8; 6.0; 6.4 units on a scale — p=0.25
Phase 4 N=31 NAS Treatment - Opiate Versus Non-Opiate
Neonatal Abstinence Syndrome
Primary: Finnegan Neonatal Abstinence Scoring System — 7.5; 8.5; 6.6; 5.7 scores on a scale
Phase 2 N=91 Pharmacotherapy & CM for Opioid and Cocaine Dependence
Cocaine Dependence
Primary: Average Number of Positive Urine Tests — 32; 30.2; 28.1; 31.4 urine tests
N/A N=37 An Efficacy and Safety Trial of Intranasal Ketorolac in Emergency Department Patients for the Treatment of Acute Pain
Other Acute Pain
Primary: Efficacy of Intranasal Ketorolac on Numeric Pain Scale — 10; 2; 12; 5 Participants
N/A N=20 Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain
Vertebral Artery Dissection · Cerebrovascular Accident · Stroke
Primary: Changes in Blood Flow Through the Vertebral Artery and Posterior Cerebral and Cerebellar Circulation — 15.5; 15.1; 14.7 cm/s
N/A N=20 Sleep and Immunity in Rheumatoid Arthritis : Remicade Substudy
Rheumatoid Arthritis
Primary: Slow Wave Sleep — 82.6; 67.3 Minutes
Phase 2 N=25 Phase II Study of RT-PEPC in Relapsed Mantle Cell Lymphoma
Non-Hodgkin's Lymphoma
Primary: Overall Survival and Progression Free Survival — 73 percentage of patients