65,437 trials
HIV Infections
Primary: WHO Anthropometric Measure of Weight-for-Age Z-Score — -0.32; -0.80; -1.59; -0.29 Z-scores
Influenza Infection
Primary: Part 1: Infectivity Rate Based on Quantitative Reverse Transcriptase-Polymerase Chain Reaction (qRT-PCR) From Day 1 PM Through Day 8 AM — 15 Participants
HPV Infection · Cervical Cancer · HIV Infections
Primary: Same-day Visual Inspection With Acetic Acid (VIA) Rate — 469; 459 Participants
Relapsed Solid Tumor · Refractory Solid Tumor
Primary: Recommended Phase 2 Dose (RP2D) of Abemaciclib in Combination With Irinotecan and Temozolomide (Part A) — 55 milligrams/squared meters (mg/m²) BID
Upper Facial Lines
Primary: Percentage of Participants With Responder Status of 'Mostly Satisfied' or 'Very Satisfied' on the Facial Line Satisfaction Questionnaire (FLSQ) Follow Up Item 4…
Recurrent Hodgkin Lymphoma · Refractory Hodgkin Lymphoma · Classical Hodgkin Lymphoma
Primary: Maximum Tolerable Dose (Phase I) — NA Participants
Type 2 Diabetes · T2D
Primary: Change From Baseline in Hemoglobin A1c (HbA1c) [Noninferiority Analysis] — -1.19; -1.16 Percentage of HbA1c
Heart Failure, Systolic · Inflammation
Primary: Changes in Peak Oxygen Consumption (VO2) — 1.50; 1.20 mL/kg/min — p=0.60
Drug Use Disorders · Illicit Drug Use · Alcohol-Related Disorders
Primary: Reach of the Digital Therapeutic to Patients in the Primary Care Clinic — 1; 4 Participants
C3G · IC-MPGN · C3 Glomerulopathy
Primary: Randomized Controlled Period: Change From Baseline in Log-Transformed Urine Protein-to-Creatinine Ratio (uPCR) at Week 26 — -1.114; 0.029 log (uPCR) — p=<0.0001
Pediatric: Genetic Syndrome
Primary: The Number of Subjects With a Confirmed Genetic Disorder Detected by NewbornDx — 109 Participants
Schizophrenia · Schizoaffective Disorder
Primary: Total Positive and Negative Syndrome Scale (PANSS) Score Between Baseline and 24 Weeks. — 89.0; 89.7; 80.0; 80.8 score on a scale
Pneumothorax · Tension Pneumothorax
Primary: Pleural Pressure (Ppl) Prior to Evacuation of Pleural Air — 7.44; -1.79 cmH2O
Healthy · Elderly
Primary: Maximum Human Plasma Concentration of Bioactives From Centella Asiatica. — 174; 372; 0.3; 0.5 ng/mL
Hunter Syndrome
Primary: Number of Participants With Treatment-emergent Adverse Events (TEAEs) — 4; 10; 5 Participants