N/A N=23 Positive Psychology to Improve Healthy Behaviors After an Acute Coronary Syndrome
Acute Coronary Syndrome
Primary: Rate of Exercise Completion — 17 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=419 AZD9291 (Osimertinib) Versus Platinum-Based Doublet-Chemotherapy in Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Anticancer Treatment
Primary: Progression Free Survival (PFS) by Investigator Assessment — 10.1; 4.4 Months — p=<0.001
N/A N=114 Non-invasive Ventilation Versus Continuous Positive Airway Pressure in Cardiogenic Pulmonary Edema
Cardiogenic Pulmonary Oedema
Primary: Need for an Endotracheal Intubation Within Seven Days After Onset of Cardiopulmonary Edema at the Intensive Care Unit — 5; 5 Participants — p=1.000
Phase 4 N=21 Frontal Hypoperfusion Effects on Antidepressant Outcomes in Late-Life Depression
Major Depressive Disorder
Primary: Remission of Depression — 10 Participants
N/A N=12 Inpatient Closed-loop Glucose Control
Diabetes Mellitus · Hyperglycemia
Primary: Average Blood Glucose Over the Closed-loop Control Period, as Determined From GlucoScout Measurements. — 115.9; 107.0; 124.83 mg/dl
Phase 4 N=29 Corticosteroid/Ropivacaine Versus Corticosteroid/Saline Injections for Knee Osteoarthritis
Osteoarthritis
Primary: The Knee Osteoarthritis Outcome Score (KOOS) Pain Subscale — 63.1; 67.2 units on a scale
Phase 3 N=554 Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors
Cognitive/Functional Effects · Metastatic Cancer · Neurotoxicity
Primary: Change in the Hopkins Verbal Learning Test - Revised for Delayed Recall (HVLT-R-delayed Recall) at 24 Weeks — 0; -0.9 units on a scale — p=0.059
Phase 3 N=676 Efficacy of Secukinumab Compared to Ustekinumab in Patients With Plaque-type Psoriasis
Chronic Plaque Type Psoriasis
Primary: Percentage of Participants With Moderate to Severe Plaque Psoriasis Who Achieved Psoriasis Area and Severity Index (PASI) 90 at Week 16 — 79.0; 57.3 Percentage of…
Phase 2 N=1,063 Trial to Assess Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Meningococcal ABCWY Vaccine as Compared to Meningococcal B Vaccine in Adolescents
Infections, Meningococcal
Primary: Human Serum Bactericidal Assay (hSBA) Geometric Mean Titers (GMTs) Against N. Meningitidis Serogroup B Test Strains When Administered According to 0_2 Month Schedule…
Phase 2 N=10 Acetylcholinesterase Inhibition and Orthostatic Hypotension in SCI
Hypotension, Postural
Primary: Systolic Blood Pressure — 97; 103; 90; 88 mm Hg
Phase 4 N=568 Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes
Type 2 Diabetes Mellitus
Primary: Adjusted Mean Change From Baseline in HbA1c — -0.93; -0.96 percent
Phase 3 N=54 Japanese Phase 3 Study of Aflibercept in Neovascular Glaucoma Patients
Glaucoma, Neovascular
Primary: Change in Intraocular Pressure (IOP) From Baseline to Pre-dose at Week 1 — -8.5; -4.9 mmHg — p=0.0644
N/A N=272 Study of the Consumer Use of a New Home Test to Measure Sperm Concentration
Fertility, Male · Sub-Fertility, Male
Primary: Number of Untrained Lay Users That Obtained Accurate and Inaccurate Subfertility Results From the TRAK Device When Compared to Results Obtained From the Gold Standard…
Phase 2 N=35 Sunitinib Malate in Treating Patients With Persistent or Recurrent Clear Cell Ovarian Cancer
Ovarian Clear Cell Adenocarcinoma · Recurrent Ovarian Carcinoma
Primary: Objective Tumor Response Rate (Complete and Partial Response) — 6.7 percentage of participants
N/A N=80 Computerized Brief Intervention vs. Delayed Computerized Brief Intervention
Drug Abuse
Primary: Alcohol, Smoking, and Substance Involvement Screening Tests (ASSIST) Global Continuum of Illicit Drug Risk Score — 24.4; 27.8 units on a scale