Phase 2 N=42 Enhancing Extinction Learning in Post Traumatic Stress Disorder (PTSD)
Chronic Posttraumatic Stress Disorder
Primary: PTSD Symptom Severity-Interview (PSS-I) — 32.07; 31.38; 32.73; 17.10 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=27 Phase III Study of Coagulation FVIIa (Recombinant) in Congenital Hemophilia A or B Patients With Inhibitors
Hemophilia A With Inhibitors · Hemophilia B With Inhibitors
Primary: Proportion of Successfully Treated Mild/Moderate Bleeding Episodes — .849; .932 Proportion of Success of BEs
Phase 2 N=291 Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors
Childhood Renal Cell Carcinoma · Clear Cell Renal Cell Carcinoma · Clear Cell Sarcoma of the Kidney
Primary: Event-Free Survival of Patients With Diffuse Anaplastic Wilms' Tumor (DAWT) — 76.1; 25.0; 87.5 Percentage of 4-year OS — p=.0199
N/A N=80 Posterior Capsular Injection With Femoral Nerve Block for Total Knee Arthroplasty
Posterior Knee Infiltration
Primary: Pain Intensity — 3.5; 3.2; 2.1; 1.5 pain score
Phase 2 N=31 A Study of Oral N-Acetylcysteine in Children With Autism Spectrum Disorders
Autistic Disorder · Asperger Syndrome · Child Development Disorders, Pervasive
Primary: Clinical Global Impression - Severity — 0; 0; 0; 0 Participants
Phase 4 N=285 BLIS - Breastfeeding Levonorgestrel IUD Study
Contraception
Primary: Breastfeeding Continuation Rates at 8 Weeks Postpartum — 88; 86 Participants
Phase 4 N=218 Spinal Cord Stimulation for Predominant Low Back Pain
Failed Back Surgery Syndrome · Back Pain · Pain in Leg, Unspecified
Primary: Compare Proportion of Subjects With ≥50% Reduction in Low Back Pain Intensity Between the Treatment Groups — 15; 5 Participants — p=0.036
Phase 3 N=349 SonoVue®-Enhanced Ultrasound Versus Unenhanced US for Focal Liver Lesion Characterization
Liver Neoplasms
Primary: Sensitivity: Percentage of True Positive Lesions Among All Malignant Lesions Per Truth Standard — 53.2; 64.5; 41.1; 60.5 Percentage of true positive lesions — p=0.0754
N/A N=14 Blood Volume Analysis of Total Hip Arthroplasty Patients Under Hypotensive Anesthesia
Blood Volume Analysis
Primary: Change in Total Blood Volume — 487 ml
Phase 3 N=800 05-001: Treatment of Acute Lymphoblastic Leukemia in Children
Drug/Agent Toxicity by Tissue/Organ · Leukemia
Primary: Asparaginase-Related Toxicity Rate — 26; 28 percentage of participants — p=.60
Phase 3 N=40 Efficacy of EUS-guided Celiac Plexus Blockade in Chronic Pancreatitis
Chronic Pancreatitis
Primary: Change in Pain Disability Index — 3; 3 Participants
Phase 4 N=60 Effect of Low Dose Corticosteroids on Perioperative Markers of Thrombosis and Fibrinolysis in Total Knee Arthroplasty
Total Knee Arthroplasty
Primary: Prothrombin Fragment (PF1.2), a Marker of Thrombin Generation — 263.6; 266.5; 935.8; 615.9 pMol/L
Phase 3 N=983 Prevention of Adult Caries Study (PACS)
Caries, Dental
Primary: Total Net D12FS Caries Increment (Total of Non-cavitated Lesions (D1), Cavitated Lesions (D2) and Sound Surfaces (S)) — 2.43; 2.68 weighted increment units/13 months…
Phase 2 N=13 A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance
Enteral Feeding Intolerance
Primary: Adverse Events — 5; 4 participants
N/A N=211 REASSURE AV Registry
Sudden Cardiac Death · Bradycardia
Primary: Inappropriate Shock Free Rate — 97.2 % of shock free rates