Phase 4 N=50 Dexmedetomidine vs Propofol TIVA (Total Intravenous Anesthesia) and Interscalene Block
Shoulder Pain
Primary: Number of Participants That Need an Airway Intervention. — 0; 5 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=270 Helping Those With Mental Illness Quit Smoking
Smoking · Nicotine Dependence · Mental Disorders
Primary: Acceptance of Wisconsin Tobacco Quit Line Services — 11; 6; 6 participants
Phase 4 N=602 Study of a Single Dose or Two Doses of a Trivalent Inactivated Influenza Vaccine Produced at Shenzhen, China
Influenza
Primary: Geometric Mean Titers of Influenza Antibodies Before and Following Vaccination With a Trivalent Inactivated Influenza Vaccine — 12.8; 24.3; 11.2; 9 Titers (1/dilution)
Phase 4 N=32 Reducing Risk of Type 2 Diabetes: Hydroxychloroquine Use in Pre-Diabetes
Pre-diabetes
Primary: Insulin Sensitivity — 0.08; -0.11 10^-4/pmol*l/min — p=<0.01
Phase 4 N=54 Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic Regulation
Major Depressive Disorder · Suicidal Ideation
Primary: Mean Score of Beck Scale for Suicidal Ideation of Three Treatment Groups (Paliperidone, Lithium and Placebo) After 3 Months of Treatment — 22.1; 22.1; 21.3 units on a…
Phase 4 N=90 Quetiapine for Bipolar Disorder and Alcohol Dependence
Bipolar Disorder · Alcohol Dependence
Primary: The Number of Standard Drinks/Day Will Serve as the Primary Outcome Measure. — 10.6; 8.09 drinks — p=0.4709
Phase 4 N=13 Ability of Mayo Clinic High-performance Liquid Chromatography (HPLC) Method to Measure Fecal Bile Acids
Diarrhea Predominant Irritable Bowel Syndrome
Primary: Change in Total 48 Hour Fecal Bile Acids (BA) From Baseline in Response to Treatment With Colesevelam — 1662; 3496 uM — p=0.012
Phase 4 N=463 Bupropion SR Plus Counseling for Smoking Cessation
Tobacco Dependence · Smoking
Primary: 7-day Point Prevalence Abstinence From Smoking at 6 Months — 21; 16; 15; 14 Number of abstinent participants — p=>0.05
Phase 4 N=28 A Clinical Trial to Study the Effects of Two Drugs, Lycopene and Prednisolone in Patients With Oral Lichen Planus
Oral Lichen Planus
Primary: Change in Severity of Lesions(Degree of Reticular, Erythematous and Ulceration) by Using Piboonniyom REU Severity Score — 2.15; 0.73 Scores on a scale — p=0.004
Phase 4 N=32,175 Effectiveness, Safety and Immunogenicity of GSK Biologicals' HPV Vaccine GSK580299 (Cervarix) Administered in Healthy Adolescents
Infections, Papillomavirus
Primary: Number of Female Subjects With Overall Vaccine Effectiveness Against Genital Infection With Human Papilloma Virus (HPV)-16/18 Types in Cervarix/Engerix-B B Group Versus…
Phase 4 N=150 A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With HBeAg Positive Chronic Hepatitis B.
Hepatitis B, Chronic
Primary: Percentage of Participants With Hepatitis B Virus DNA <100,000 Copies/mL At Week 72 — 20.9; 21.9 percentage of participants
Phase 4 N=12 An Open, Non-comparative Study of the Efficacy and Safety of Treatment of Acne Scars With Restylane Vital Lidocaine
Acne Scars
Primary: Evaluation of Acne Scarring and the Surrounding Skin Using the Global Aesthetic Improvement Scale — 100 percentage of participants
Phase 4 N=643 Safety and Efficacy Study to Evaluate Denosumab Compared With Zoledronic Acid in Postmenopausal Women With Osteoporosis
Post Menopausal Osteoporosis
Primary: Percent Change From Baseline in Lumbar Spine Bone Mineral Density at Month 12 - Non-inferiority Analysis — 1.1; 3.2 percent change — p=<0.0001
Phase 4 N=1,469 ACCELERATE Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With COPEGUS (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C (CHC) Infection.
Hepatitis C, Chronic
Primary: Percentage of Participants With Sustained Virological Response (SVR) — 65; 76 percentage of participants — p=<.0001
Phase 4 N=26 A Study of Quetiapine SR (Seroquel SR) to Treat SSRI-Resistant, Comorbid Panic Disorder Patients
Panic Disorder
Primary: Change in Mean Total Panic Disorder Severity Scale (PDSS) Scores — -5.3; -5.6 units on a scale