Phase 3 N=4 Sorbent Therapy of the Cutaneous Porphyrias
Erythropoietic Protoporphyria
Primary: Photosensitivity, Assessed by Measuring the Number of Minutes of Sun Tolerance — 65.8 minutes
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=127 Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics
Psychotic Disorders
Primary: Body Mass Index (BMI) Z-score Change — 0.040; -0.112; -0.088 Z Score
Phase 4 N=50 Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method
Arrhythmia, Cardiac · Kidney Cancer · Surgery
Primary: Incidence of Perioperative Cardiac Arrhythmias Evaluated by a Continuous ECG Holter Monitoring in the Perioperative Period — 6; 6; 18; 16 Participants — p=0.3861
N/A N=106 Ultrasound Guided Technique for Internal Jugular Central Venous Catheterization in Pediatric Cardiac Surgical Patients
Accidental Puncture of Artery During Catheter Insertion
Primary: Number of Attempts for Successful Central Venous Cannulation — 1.29 Attempts
Phase 2 N=171 Phase II Single Arm Study of AZD9291 to Treat NSCLC Patients in Asia Pacific
Non-Small Cell Lung Cancer
Primary: ORR According to RECIST 1.1 by Independent Review — 62.0 % of participants
N/A N=142 Study Investigating Efficacy of an Occluding Dentifrice for Dentine Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 14 — -1.01; -0.88 score on a scale — p=0.5191
Phase 3 N=488 Child and Adolescent Anxiety Disorders (CAMS)
Anxiety Disorders · Social Phobia · Generalized Anxiety Disorder
Primary: Clinical Global Impression - Improvement Scale — 54.9; 59.7; 80.7; 23.7 percentage of participants
Phase 3 N=255 DHEA Against Vaginal Atrophy - 3-Month Efficacy Study
Vaginal Atrophy
Primary: Change From Baseline to Week 12 in Percentage of Parabasal Cells in the Maturation Index of the Vaginal Smear — 68.48; 65.72; 65.05; 66.86 Percentage of parabasal cells
Phase 3 N=1,100 Immunogenicity and Safety Study of GlaxoSmithKline Biologicals' Poliorix™ Vaccine
Poliomyelitis · Poliomyelitis Vaccines
Primary: Number of Seroprotected Subjects Against Poliovirus Types 1, 2 and 3 — 306; 296; 306; 296 Participants
Phase 2 N=25 A Study of Belimumab in the Prevention of Kidney Transplant Rejection
Transplantation, Organ
Primary: Change From Baseline in naïve B Cells From Baseline to Week 24 — 4.0; -30.4 cells/mm^3
N/A N=30 Induced and Controlled Dietary Ketosis as a Regulator of Obesity and Metabolic Syndrome Pathologies
Metabolic Syndrome · Diabetes Mellitus, Type 2 · Pre Diabetes
Primary: Hemoglobin A1c — -.42; -0.37; 0.02 % of hemoglobin — p=0.001
N/A N=26 Pharmacogenetics of Metformin Action in PCOS
Polycystic Ovary Syndrome
Primary: Number of Responders/Non-responders for Each STK11 rs8111699 Genotype (C/G, C/C, G/G) — 6; 7; 5; 3 participants
Phase 2 N=116 Proteomic Profiling in Predicting Response in Patients Receiving Erlotinib for Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
Lung Cancer
Primary: Pre-treatment Tumor Proteomic Profile as a Predictor of Response, Stable Disease, or Progressive Disease
N/A N=135 Starting Pediatric Obesity Prevention in Pregnancy
Obesity · Pregnancy
Primary: Gestational Weight Gain — 0; 0; 0; 0 Participants
Phase 2 N=25 A Study of Abicipar Pegol in Japanese Patients With Neovascular Age-related Macular Degeneration
Macular Degeneration
Primary: Change From Baseline in Best Corrected Visual Acuity (BCVA) in the Study Eye — 58.5; 54.3; 55.8; 8.9 Letters