65,437 trials
Depression
Primary: Depressive Symptoms at 4 Weeks — 15.6; 15.6 units on a scale — p=0.16
Asthma · Atopy
Primary: Percentage Change in the Ratio of Mean-normalized Perfusion Within Ventilation Defective Regions Relative to Outside — -17.8 percentage
Common Cold
Primary: Interleukin-8 (IL-8) — 133; 122 pg/ml
Pre-Diabetes
Primary: Change in Serum Fructosamine in Subjects Treated With Low Dose and High Dose BTI320 Compared With Placebo — -5.2; -9.4; -8.8 umol/L — p=0.57
Pruritis
Primary: Investigator Global Assessment — 2.63; 2.32 units on a scale
Asthma
Primary: Treatment Failure — 38; 39; 45 participants
Visual Performance
Primary: Subjective Overall Comfort — 65.0; 53.6; 61.9 units on a scale
Infections, Urinary Tract
Primary: Maximal Measured Plasma Concentration (Cmax) After a Single Dose — 28.18; 29.20 Microgram per milliliter
Dystrophic Epidermolysis Bullosa
Primary: Percent Change of Active Blisters and in Total Blister/Erosion Counts — -29.6 percent change — p=0.82
Malignant Pleural Effusion · Recurrent Non-small Cell Lung Cancer · Stage IIIB Non-small Cell Lung Cancer
Primary: Overall Response Rate (Complete and Partial Responses) as Assessed by RECIST Criteria — 11 Participants
Postoperative Nausea and Vomiting
Primary: The Incidence of Postoperative Nausea and Vomiting — 5; 18 Participants — p=<0.05
Smoking, Marijuana
Primary: Mood Scale - Subscale 'Feeling High' — 4.35; 2.48; 0.39; 6.55 units on a scale VAS 1-100 mm
Healthy
Primary: AUC0-inf for Total Dabigatran — 599; 1050; 928 ng(nanogram)*h(hour)/mL(milliliter)
Gout
Primary: Maximum Observed Plasma Concentration (Cmax) — 25.6; 29.0; 38.2; 16.7 ng/mL
Left Ventricular Dysfunction
Primary: Change in Left Ventricular Ejection Fraction From Baseline to 2 Years (Intent to Treat Cohort). — -2.29; -3.43 percentage — p=0.4347