Phase 1 N=155 AZD8108 SAD/MAD in Healthy Volunteers
Healthy Volunteers
Primary: Safety Laboratory - Thyroid Stimulating Hormone Above Upper Limit of Normal — 2; 3; 0; 0 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=64 Baclofen as Add-On to Standard Treatment of Alcohol- Dependent Patients
Alcohol Dependence
Primary: Percent Abstinent Days — 40; 36 percentage of abstinent days
Phase 2 N=84 A Study to Investigate Effects of Omega-3 Carboxylic Acids and Dapagliflozin on Liver Fat Content in Diabetic Patients
T2 Diabetes and Fatty Liver Disease (Non-alcoholic Origin)
Primary: Change From Baseline to Week 12 in % Liver Fat as Assessed by MRI (Comparison Versus Placebo) — 0.79; 0.97 ratio of % liver fat — p=0.046
Phase 2 N=88 Anastrozole Administration in Elderly Hypogonadal Men
Hypogonadism
Primary: Change in Lean Body Mass — -2000; -1500 grams
N/A N=9 Evaluation of Non-Ablative Laser for Treatment of Direct Brow Lift Scars
Scar
Primary: Relative Improvement — 50.0; 50.0 percentage of times treated scar chosen
N/A N=100 Potential of an Experimental Mouthwash Formulation to Reduce Dry Mouth Symptoms
Xerostomia
Primary: Mean Response to the Question 1 'Relieving the Discomfort of Dry Mouth' in Product Performance and Attributes Questionnaire 3 (PPAQ3) at 120 Minutes(Mins) Post Treatment…
N/A N=195 Connect.Parkinson: Connecting Individuals With Parkinson Disease to Specialists in Their Homes
Parkinson Disease
Primary: Feasibility of Virtual Visits for Parkinson Disease — 0; 95 participants
Phase 4 N=36 A PK/PD Study of Fospropofol Disodium Compared With Propofol Injectable Emulsion
Anesthesia
Primary: Area Under the Plasma Concentration-Time Curve From Time 0 to Infinity of Fospropofol (AUC(0-inf)) — 16522; 25052; 36629 ug.h/L
N/A N=202 Solitaire FR Thrombectomy for Acute Revascularisation
Stroke, Acute
Primary: Arterial Recanalization of the Occluded Target Vessel Measured by Thrombolysis in Cerebral Infarction (TICI) Score Equal or Superior to 2b Following the Use of the Study…
Phase 3 N=130 Corneal Collagen Cross-Linking for Ectasia (CXL)
Ectasia
Primary: Mean Change From Baseline in Maximum Keratometry (Kmax) — -0.5; 0.5 diopters
Phase 3 N=219 Intercalating and Maintenance Use of Iressa Versus Chemotherapy in Selected Advanced Non Small Cell Lung Cancer
Non-small Cell Lung Cancer
Primary: Progression Free Survival — 9.7; 4.2 months
N/A N=51 The Effects of Broccoli Sprout Extract on Obstructive Lung Disease
Asthma · COPD
Primary: The Primary Outcome is the Change in Bronchodilation and Bronchoprotection After Broccoli Sprout Extract — 10.3; 26.7 index
Phase 3 N=327 MK-0954E Study in Participants With Hypertension (MK-0954E-357)
Hypertension
Primary: Change in Mean Trough Sitting Diastolic Blood Pressure (SiDBP) — -9.1; -8.0 mmHg — p=0.205
Phase 2 N=111 Iodine I 131 Tositumomab, Etoposide and Cyclophosphamide Followed by Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Anaplastic Large Cell Lymphoma · Cutaneous B-cell Non-Hodgkin Lymphoma · Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
Primary: Progression-free Survival — 56 percentage of participants
Phase 4 N=117 Study to Evaluate the Effect of BYDUREON on 24-hour Glucose Control in Metformin Treated Patients With Type 2 Diabetes.
Type 2 Diabetes
Primary: Change in 24-hour Mean Weighted Glucose — 185.7; 183.8; 158.3; 176.9 (mg/dL) — p=<0.001