65,437 trials
Type 2 Diabetes
Primary: Incremental Area Under the Plasma Glucose (BG) Concentration-time Profile (AUC) — 5678; 5557 [mg*min/dL]
Dental Anxiety
Primary: Change in Modified Dental Anxiety Scale — 19.5; 19.6; 15.4; 17.6 units on a scale — p=<0.05
Diabetes Mellitus, Type I
Primary: Insulin Independence With Both an HbA1c ≤ 6.5% and no Severe Hypoglycemic Events at 1 Year After the First Islet Transplant or a Reduction in HbA1c of at Least 1 Point…
Breast Cancer
Primary: Progression-free Survival (PFS)Assessed by Local Investigator's Assessment (Phase ll) — 8.0; 9.2 Months
Schizophrenia
Primary: Change in MATRICS Consensus Cognitive Battery Composite Score Change — 1.3; 2.3; -0.2 units on a scale
Varicose Veins
Primary: Efficacy in Treating Reticular Veins by Photographs: Mean Percent Reticular Vein Disappearance Two Months After Treatment. — 95.17; 85.40 % of Reticular Veins that…
Irritable Bowel Syndrome · Constipation
Primary: Change in Gastric Emptying Time, Small Bowel Transit Time, Colon Transit Time and Whole Gut Transit Time From Baseline — 5.49; 6.52; -0.16; 0.2 hours
Ankylosing Spondylitis
Primary: Assessment of Responders for the SpondyloArthritis International Society / ASAS 20 Response — 59.7; 60.8; 28.7 % responders — p=<0.0001
Advance Directive Completion
Primary: Proportion of Participants That Select to Complete an Advance Directive — 0.35; 0.20 proportion of participants
Ischemic Stroke
Primary: Maximum Expiratory Pressure — 104.31 cm H2O (pressure measurement) — p=.001
Congenital Hemophilia A
Primary: Treatment Success — 96.3 Percentage of treated bleeding events
Obstructive Sleep Apnea
Primary: AHI — 19.2; 19.3 events/hour — p=>0.05
B-cell Adult Acute Lymphoblastic Leukemia · B-cell Childhood Acute Lymphoblastic Leukemia · Recurrent Adult Acute Lymphoblastic Leukemia
Primary: Second Complete Remission Rate at the End of Block 1 Reinduction Chemotherapy — 72.2; 63 Percentage of participants
Sedation
Primary: Number of Participants With Sub-clinical Respiratory Depression and Clinical Events Associated With Respiratory Depression During the Sedation Procedure — 11; 12…
Obsessive-Compulsive Disorder
Primary: Clinical Improvement (Yale-Brown Obsessive Compulsive Scale/Y-BOCS) — 36; 9 percentage of participants — p=<0.05