N/A N=84 Airway Microbiome in Asthma: Relationships to Asthma Phenotype and Inhaled Corticosteroid Treatment
Asthma · Atopy
Primary: Microbial Community Richness — 449; 543; 483; 444 number of bacterial taxa
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=22 Pharmacokinetic, Efficacy, and Safety Study of Octafibrin Compared to Haemocomplettan/Riastap
Congenital Fibrinogen Deficiency · Afibrinogenemia
Primary: Ratio of Octafibrin/FIBRYGA® to Haemocomplettan® P/RiaSTAP(TM) for Fibrinogen Activity Normalized Area Under the Curve Unstandardized — 1.196 ratio
N/A N=100 A Prospective, Multi-center, Observational Study of the Use of Permacol™ Collagen Paste to Treat Anorectal Fistulas
Anorectal Fistulas
Primary: Fistula Healing in Patients at 6 Months Following Surgery — 56.7; 43.3 percentage of participants
Phase 4 N=20 Interferon Alfa Sensitivity in HIV/HCV Persons Before and After HIV Meds
HIV Infection · Hepatitis C
Primary: HCV RNA — 0.65; 0.81 log IU/ml
Phase 2 N=600 Immunogenicity and Safety of Sanofi Pasteur's CYD Dengue Vaccine in Healthy Children and Adolescents in Latin America
Dengue · Dengue Hemorrhagic Fever · Dengue Virus
Primary: Percentage of Participants With Antibody Titers of ≥10 1/Dil Against Each Parental Dengue Virus Serotype Strain Before and Following Each Injection With Sanofi Pasteur's…
N/A N=28 Individual Differences in the Response to Drugs
Healthy
Primary: Change in General Drug Effects (Drug Effects Questionnaire) at 30 Minutes After Capsule Administration — 4.79; 12.83; 11.08; 12.17 units on a scale
Phase 2 N=116 Vitamin D3 Effects on Musculoskeletal Symptoms With Use of Aromatase Inhibitors
Muscle Pain · Joint Pain
Primary: Change in Musculoskeletal Symptom Sub-scale on the Breast Cancer Prevention Trial Symptom Scale — -0.2; -0.5 units on a scale — p=0.38
Phase 3 N=250 Study of a Single Primary Dose Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (IMOJEV®) in Healthy Subjects
Japanese Encephalitis
Primary: Number of Participants With Solicited Injection Site Reactions and Systemic Events Following a Single Primary Dose of a Live Attenuated Japanese Encephalitis Chimeric…
N/A N=92 German Adaptation of REACH II
Dementia · Family Caregiver
Primary: Change From Baseline in Burden on the German Version of Zarit Caregiver Burden Interview (ZBI) (5-point Scale) at Month 6 — -0.43; 7.05 units on a scale — p=<0.001
Phase 2 N=217 Patient Anxiety During Radiological Examination
Anxiety
Primary: Change in Anxiety as Measured by Visual Analog Scale — 3.4; 2.1; 1.6; 1.9 units on a scale — p=<0.001
N/A N=170 Study Cyclosporine (CsA) Versus Tacrolimus (Tacro) After Campath Induction in Kidney Transplantation
Acute Graft Rejection · Chronic Allograft Nephropathy · Polyomavirus-related Transplant Nephropathy
Primary: Patient Survival — 96.4; 96.3 percentage of participants
N/A N=32 Alice PDx User/Validation Extended Trial
Sleep Apnea · Sleep-Disordered Breathing
Primary: This Study Will Compare the Apnea Hypopnea Index Recorded by the Alice PDx to the Physiological Data Recorded by Its Predicate Device the Alice 5 System and Validate Its…
Phase 3 N=42 Expiratory Muscle Training for Persons With Neurodegenerative Disease
Parkinson's Disease · Multiple Sclerosis
Primary: Maximum Expiratory Pressure (MEP) — 78.6; 75.56; 99.00; 99.38 cm H2O — p=0.899
Phase 3 N=309 Add-on to Micamlo BP Trial
Hypertension
Primary: Change From Baseline in Mean Seated DBP at Trough After 8 Weeks of the Double-blind Period. — -8.4; -4.5 mmHg — p=<0.0001
N/A N=25 Effect of Intraarticular Steroids on Bone Turnover in Osteoarthritis
Osteoarthritis
Primary: Change in Serum Osteocalcin — -2.18; -0.45; -1.10 ng/mL