Phase 1 N=16 Study on Sapropterin Dihydrochloride Oral Suspension in Healthy Subjects
Bioavailability
Primary: Uncorrected Sapropterin AUC0-t — 989.77; 837.20; 835.52; 791.64 hr*ng/mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=228 CORIMUNO-19 - Tocilizumab Trial - TOCI (CORIMUNO-TOCI)
Corona Virus Infection
Primary: Percentage of Participants With WHO Clinical Progression Scale > 5 at Day 4 -- Severe COVID Population (WHO Clinical Progression Scale =5 at Baseline) — 19; 28…
N/A N=44 The Effects of Added Sugar Intake on Brain Blood Flow and Hippocampal Function in Midlife Adults
Aging · Healthy Diet
Primary: Arterial Compliance (m^2 Kilopascal^-1) — 0.824; 0.772 m^2 kilopascal^-1
N/A N=500 Fresh Food Farmacy: A Randomized Controlled Trial
Type 2 Diabetes
Primary: HbA1c — 8.781177; 8.814526 % of hemoglobin — p=0.8638688
N/A N=60 Comparison Effects Of Different Exercise Approaches On Type 2 DM Women
Type 2 Diabetes
Primary: Glycosylated Hemoglobin Change — 6.82; 7.17; 6.80; 6.33 percentage of glycosylated hemoglobin — p=0.830
Phase 2 N=21 Hypofractionated Boost Before Chemoradiation for Patients With Stage II-III Non-small Cell Lung Cancer Unsuitable for Surgery
Recurrent Non-small Cell Lung Cancer · Stage IIA Non-small Cell Lung Cancer · Stage IIB Non-small Cell Lung Cancer
Primary: Primary Tumor Control Rate, as Measured From the Time of Treatment Completion Until the First Documented Date of Local Failure — 100 percentage of participants
N/A N=36 Green Sun Medical Dynamic Scoliosis Brace
Adolescent Idiopathic Scoliosis
Primary: Percentage of Participants With Acceptable GSM In-Brace Correction — 100 Percentage acceptable GSM correction
Phase 3 N=62 Three Drug Combination Therapy Versus Conventional Treatment of Children With Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia (CAH)
Primary: Adult Height Relative to General Population — -0.34; -0.6 Standard Deviation Score (SDS) units
Phase 1 N=20 Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-cell Malignancies
Cutaneous T-Cell Lymphoma · Mature T-cell Malignancies · Peripheral T-Cell Lymphoma
Primary: Maximum Tolerated Dose (MTD) — 20 mg/day
N/A N=112 Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed Adolescents
Major Depressive Disorder
Primary: Hamilton Depression Rating Scale-24(HAMD24) Total Score Change From Baseline Value. — -11.1; -10.6 score on a scale
N/A N=52 Anatomical Shoulder™ Fracture PMCF Study
Fracture
Primary: Functional Performance — 57.7 score on a scale
N/A N=118 Microcurrent Device (TIVIC Health)
Chronic Rhinosinusitis
Primary: Change in Pain Visual Analog Score After First Use of Device — 4.9; 5.6; 4.7; 4.8 score on a scale
Phase 4 N=60 The Role of Chlorhexidine in Minimizing the Viral Load Among COVID-19 Patients
COVID-19
Primary: E Genes — 28.50; 27.33; 30.28; 27.80 Cycle
Phase 2 N=57 Multi-Arm Study to Test the Efficacy of Immunotherapeutic Agents in Multiple Sarcoma Subtypes
Advanced and/or Metastatic Sarcoma
Primary: Progression-Free Survival (PFS) — 0.17; 0.3; 0.4; 0.8 proportion of participants
Early Phase 1 N=95 Zinc Effect on Inflammation and Cardiovascular Risk in HIV
Inflammation · Cardiovascular Diseases · Zinc Deficiency
Primary: Effect of Zinc Supplementation on Zinc Levels at 24 Weeks in HIV-infected Subjects — 8.60; 33.50 absolute change (μg/dL) — p=<0.01