N/A N=101 VR Simulation and Basic Skills in THA
Educational Problems · Hip Arthroplasty · Osteoarthritis, Hip
Primary: Medical Students Surgical Skills Differences Between VR and Control Group. — 51.5; 59.1; 115.9; 201.5 degrees — p=<0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=132 The Impact of Different Skin Suture Methods in Episiotomy Repair on Healing and Pain
Labor; Prolonged, Second Stage · Episiotomy Wound
Primary: Healing by Redness, Edema, Ecchymosis and Discharge (REEDA) Score — 1; 1; 0 REEDA Score
Phase 2 N=348 Dose-Adjusted EPOCH Chemotherapy and Rituximab (CD20+) in Previously Untreated Aggressive Non-Hodgkin's Lymphoma
Diffuse Large B-Cell Lymphoma (DLBCL) · Primary Mediastinal Large B-cell Lymphoma · Burkitt Lymphoma
Primary: Overall Response (Complete Response + Partial Response) — 216; 94 Participants
Phase 1 N=50 A Study on the Reactogenicity, Safety and Immune Response of a Targeted Immunotherapy Against HSV in Healthy Japanese Participants Aged 18-40 Years
Herpes Simplex
Primary: Number of Participants Reporting Any Solicited Administration Site Events — 8; 2; 0; 19 Participants
N/A N=32 The RELISH Study: Compliance and Palatability of Oral Nutritional Supplements in Hospitalised Older Adults
Malnutrition
Primary: Percentage of the Mean Oral Nutritional Supplement Consumed Per Day (%) — 26.31; 66.8 percentage of supplement consumed — p=0.01
Phase 1 N=18 A Study to Understand the Effect of Tablet Formulation and Food on PF-06821497 in Healthy Adult Participants.
Healthy
Primary: Area Under the Plasma Concentration-time Profile From Time 0 Extrapolated to Infinite Time (AUCinf) of PF-06821497 — 3302; 3375; 3479; 11220 ng*hr/mL
N/A N=136 Dental Implants With a SLActive® vs. SLA® Surface
Partially Edentulous Patients
Primary: Bone Level Change 12 Months After Implant Loading — 0.214; 0.056 mm — p=0.074
N/A N=20 Investigation of a New Rectal Catheter for Users of Transanal Irrigation
Bowel Management
Primary: Was it Possible to Perform Transanal Irrigation? — 20; 20 Number of participants who replied YES
Phase 2 N=319 A Study of the Safety and Efficacy of SP-624 in the Treatment of Adults With Major Depressive Disorder
Major Depressive Disorder
Primary: Change From Baseline to Week 4 in Montgomery Asberg Depression Rating Scale (MADRS) Total Score — -12.6; -10.8 Score on a scale — p=0.133
Phase 2 N=122 European Trial on Enhanced DNA Repair Inhibition in Ovarian Cancer
Ovarian Cancer · Fallopian Tube Cancer · Primary Peritoneal Carcinoma
Primary: Progression-free Survival — 8.85; 8.32 months
N/A N=40 Probing Cortical Excitability and Cognitive Function With TMS
Cognitive Dysfunction
Primary: Cortical Excitability: Resting Motor Threshold (RMT). — 51.1; 51.8 % of Max Stimulation Output (MSO)
Phase 2 N=25 Pembrolizumab in Ultramutated and Hypermutated Endometrial Cancer
Recurrent Endometrial Cancer
Primary: Frequency of Objective Tumor Response as Assessed by RECIST 1.1- Overall Response Rate (ORR) — 5; 9; 7; 3 Participants — p=0.024
Phase 4 N=71 Study of Lorlatinib In People With ALK-positive Non-small Cell Lung Cancer
Carcinoma · Non-Small-Cell Lung
Primary: Percentage of Participants With Confirmed Overall Objective Response (OR) as Per Independent Central Review (ICR) as Assessed by RECIST v1.1 — 42.3 Percentage of…
N/A N=30 Equity Using Interventions for Pain and Depression - Pilot Study
Chronic Pain · Depression · Health Equity
Primary: Change From Baseline Brief Pain Inventory (BPI) Interference Scale at 3 Months — -1.02; -0.30 units on a scale
N/A N=63 Non-Operative Management and Early Response Assessment in Rectal Cancer
Adenocarcinoma of the Lower Rectum
Primary: Clinical Complete Response Rate — 36; 2 Participants