Phase 4 N=76 Carbetocin Versus Oxytocin and Hemodynamic Effects
Effects of; Anesthesia, in Pregnancy
Primary: Cardiac Output — 96; 82; 43 percentage change in cardiac output
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=250 Immunogenicity and Safety of Rabies Vaccine, Administered With Two Different Simulated Post Exposure Schedules
Rabies
Primary: Geometric Mean Rabies Virus Neutralizing Antibody (RVNA) Concentration in Each of the Zagreb and Essen Groups on Study Day 14 — 0.09; 0.099; 12; 12 IU/mL
Phase 4 N=55 Using Santyl on Diabetic Foot Ulcers
Diabetic Foot Ulcers · Diabetic Foot Wounds
Primary: Mean Percent Change in Wound Area — -68; -36; -61; -46 percentage of change in wound area
Phase 4 N=121 A Randomized Study of Sativex on Cognitive Function and Mood: Multiple Sclerosis Patients
Multiple Sclerosis · Spasticity
Primary: Change From Baseline to the End of Treatment in Paced Auditory Serial Addition Test (PASAT) Total Score. — 6.8; 6.8 units on a scale
Phase 4 N=157 Phase IV Long-term Maintenance Study of Aripiprazole in the Treatment of Irritability Associated With Autistic Disorder
Irritability Associated With Autistic Disorder
Primary: Percentage of Patients Relapsing by Week 16 — 32; 50 Percentage of participants — p=0.097
Phase 4 N=21 Symptom Management After Breast Cancer Surgery
Neuropathic Pain · Postmastectomy Pain
Primary: Change in Pain Intensity on an 11-point Scale From Baseline to 12 Weeks — 4.0 units on a scale
Phase 4 N=30 Duloxetine Treatment in Elderly With Dysthymia
Depression · Dysthymic Disorder
Primary: Change in Hamilton Rating Scale for Depression (HAM-D, 24-item) From 0 Weeks to 12 Weeks. — 8 units on a scale — p=<0.001
Phase 4 N=87 A Study of the Comparable Efficacy and Safety of Pulmozyme (Dornase Alfa) Delivered by the eRapid Nebulizer System in Patients With Cystic Fibrosis
Cystic Fibrosis
Primary: Stability of Lung Function: Percent Predicted Forced Expiratory Volume in 1 Second (FEV1) — 98.1; 97.2 percent predicted
Phase 4 N=456 Trial to Assess Lacosamide as the First add-on Anti-epileptic Drug Treatment in Patients With Partial-onset Seizures
Partial Epilepsies
Primary: The Proportion of Subjects Who Achieved "Seizure-free Status" During the First 12 Weeks of the Maintenance Phase — 37.5; 14.9 percentage of subjects
Phase 4 N=163 Suppressive Therapy With Oral Antibiotics for Prevention of Postoperative Urinary Tract Infection (UTI)
Urinary Tract Infection
Primary: Urinary Tract Infections — 18; 10 participants
Phase 4 N=768 Immune Responses in Adults to Revaccination With ADACEL® 10 Years After a Previous Dose
Pertussis · Tetanus · Diphtheria
Primary: Percentage of Participants With Seroprotection Against Tetanus and Diphtheria Before and After Revaccination With ADACEL® 10 Years After a Previous Dose — 45; 49; 100…
Phase 4 N=110 Pharmacodynamic Evaluation of Switching From Ticagrelor to Prasugrel in Subjects With Stable Coronary Artery Disease
Coronary Artery Disease
Primary: P2Y12 Reaction Units — 95.0; 49.0 PRU (P2Y12 Reaction Units)
Phase 4 N=161 Utility of Trimethoprim-sulfamethoxazole Use in Skin Abscess Management
Skin Diseases, Infectious
Primary: Skin Abscess Resolution — 4; 3 participants
Phase 4 N=252 A 12-Week Study Comparing Pitavastatin 4 mg vs. Pravastatin 40 mg in HIV-Infected Subjects
Dyslipidemia
Primary: Change of Fasting Serum Low-density Lipoprotein Cholesterol (LDL-C) at 12 Weeks — 155.1; 154.6 mg/dL
Phase 4 N=90 Improvement in Pain,Function and HRQoL ( Health Related Quality of Life) in Subacute Low Back Pain: A Controlled Clinical Trial of Exercise vs NSAIDs (Nonsteroidal Antiinflammatory)
Back Pain Lower Back
Primary: Visual Analogue Scale of Pain — 47.3; 45.2 units on a scale