Phase 4 N=76 The Study of Exenatide Action on Vessel Function in Type 2 Diabetes and Prediabetes
Type 2 Diabetes Mellitus
Primary: Reactive Hyperemia Index (RHI) — 1.90; 1.79; 2.24; 1.95 ratio — p=<0.0001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=57 A Study of Oral Valcyte (Valganciclovir) in Pediatric Kidney Transplant Recipients
Kidney Transplantation, Cytomegalovirus Infections
Primary: Number of Participants With Adverse Events (AE), Serious Adverse Events (SAE) or Withdrawal Due to AEs — 56; 41; 6 Participants
Phase 4 N=60 Effects of Pravastatin on Cholesterol, Inflammation and Cognition in Schizophrenia
Schizophrenia · Schizoaffective Disorders · Schizophreniform Disorders
Primary: Change in LDL-cholesterol Between Baseline and Week 12 — -25.565; -2.913 mg/dl
Phase 4 N=312 Compare the Efficacy of Cinacalcet vs Traditional Vitamin D for Secondary Hyperparathyroidism (SHPT) Among Subjects Undergoing Hemodialysis
Hyperparathyroidism, Secondary
Primary: Percent Change From Baseline in Mean PTH During Efficacy Assessment Phase (EAP) — -7; -12.1 Percent change — p=0.346
Phase 4 N=122 Menopur Mixed Protocol
Infertility
Primary: Fertilization Rate — 63.14; 59.56 percentage of oocytes retrieved
Phase 4 N=64 Ultrasound Guided Pain Control Versus Standard Treatment in Emergency Department HIP Fracture Patients
Hip Fracture
Primary: Pain Score at 30 Minutes — 1.94; 2.05; 5.13 units on a scale — p=<.0001
Phase 4 N=15 Treatment of Resistant Nephrotic Syndrome With ACTH Gel (ACTHAR)
Treatment Resistant Nephrotic Syndrome
Primary: Significant Reduction in Proteinuria to Remission Levels During the Treatment Period (Includes Complete and Partial Remission, as Defined in the Outcome Measure…
Phase 4 N=110 REPArE: Rating Evaluations in Psoriatic Arthritis (PsA) With Etanercept (Enbrel®)
Psoriatic Arthritis
Primary: Percentage of Participants With Improvement of ≥ 0.50 Units From Baseline to Month 24 in the HAQ DI — 56.0 percentage of participants
Phase 4 N=375 Basal Bolus Versus Basal Insulin in Type 2 Diabetes Mellitus (T2DM)
Type 2 Diabetes · Hyperglycemia
Primary: Mean Blood Glucose Levels (Measured in mg/dL) at Randomization Are Compared to Mean Blood Glucose Levels After First Day of Treatment Among Subjects Treated With Basal…
Phase 4 N=334 Efficacy of Losartan + Amlodipine Compared to Amlodipine Alone in the Treatment of Uncontrolled High Blood Pressure (MK-0954F-399)
Hypertension
Primary: Change in Mean Sitting Diastolic Blood Pressure (MSDBP) at Week 8 — -10.1; -8.8 mmHg — p=0.1339
Phase 4 N=125 The Use of Statins Following a Left Atrial Catheter Ablation Procedure to Prevent Atrial Fibrillation
Atrial Fibrillation · Arrhythmia · Inflammation
Primary: Percentage of Subjects Without Symptoms of Atrial Fibrillation at 3 Months — 95; 93.5 Percentage of subjects — p=0.75
Phase 4 N=22 Combination of Paroxetine CR and Quetiapine for the Treatment of Refractory Generalized Anxiety Disorder
Anxiety Disorder
Primary: Hamilton Anxiety Scale (HAM-A) Score at Study Endpoint. — 16.27; 15.82; 13.64; 15.55 units on a scale — p=<0.05
Phase 4 N=202 A Study Evaluating Dosing Regimens for Treatment With Intravitreal Ranibizumab Injections in Subjects With Macular Edema Following Retinal Vein Occlusion
Macular Edema
Primary: Trend of Change From Baseline in the Best Corrected Visual Acuity (BCVA) Scores From Month 7 to Month 15 — 17.5; 19.7; 18.7; 21.0 Letters — p=0.5091
Phase 4 N=180 A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye Symptoms
Dry Eye Syndromes · Cataract
Primary: Tear Break-Up Time (TBUT) in the Study Eye — 8.5; 6.6 Seconds
Phase 4 N=51 Study of Raisins Versus Alternative Snacks in Patients With Type 2 Diabetes Mellitus
Diabetes Mellitus
Primary: Postprandial Glucose Levels — -6; 17 percent — p==0.024