17,261 trials
Refractory Diffuse Large B Cell Lymphoma (DLBCL) · Relapsed Diffuse Large B-Cell Lymphoma · Transformed Follicular Lymphoma (TFL)
Primary: Phase 1 Study: Number of Participants Experiencing Adverse Events (AEs) Defined as Dose Limiting Toxicities (DLTs) — 1 Participants
Barrett's Esophagus
Primary: Mean Ki67 Expression — 35.6; 307.8 cells/mm2
Dental Pain
Primary: Sum Pain Intensity Difference Scores — -2.4292; -68.0778; -68.3533; -93.3645 score on a scale
Atopic Dermatitis
Primary: Percentage of Participants With Success in the Overall Investigator's Global Assessment of Disease Severity (IGA) Score at Week 4 [Using Non-responder Imputation or Last…
Postoperative Pain
Primary: Summed Pain Intensity (SPI) Between Group A and Group C — 153.08; 267.51 score on a scale — p=<0.001
Rheumatoid Arthritis · Inflammatory Arthritis · Arthritis
Primary: GMFR (Geometric Mean Fold Rise ) in Varicella Zoster Virus (VZV) Glycoprotein Enzyme-linked Immunosorbent Assay (gpELISA) Immunoglobulin G (IgG) Levels From Baseline at…
Triple-negative Metastatic Breast Cancer
Primary: Objective Response Rate — 26 percentage of participants
Non-Small Cell Lung Cancer · Leptomeningeal Metastases · Brain Metastases
Primary: Best Overall Response Rate (ORR) of Subjects With BM — 15.4; 100; 31.3; 0 Percentage of participants (%)
COVID-19
Primary: Total Number of Serious Adverse Events (SAE) Through Study Day 14 — 0; 0 Serious Adverse Events
Cocaine Dependence
Primary: Change in Interaction of the Serotonin Receptor (5-HTR) Type-2C Cys23Ser Single Nucleotide Polymorphism (SNP) and a 5-HT2AR Antagonist on the Functional Circuitry…
Advanced Solid Tumors
Primary: Overall Response Rate (ORR) — 5.6; 0.0; 11.3; 14.3 percentage of participants
Uncomplicated Plasmodium Falciparum Malaria
Primary: Percentage of Patients With PCR-corrected Adequate Clinical and Parasitological Response (ACPR) on Day 28 — 11; 13; 15; 14 Participants
Metastatic Melanoma
Primary: Change in Immune-related Overall Response Rate (irORR) — 20 participants
B-cell Acute Lymphoblastic Leukemia
Primary: Percentage of Participants With Overall Remission Rate (ORR) as Determined by Independent Review Committee (IRC) Assessment. — 82.3; 100.0 Percentage of participants…
Central Neuropathic Pain · Multiple Sclerosis
Primary: Association Between the Dextromethorphan Plasma Concentration and the Change From Baseline Pain Rating Scale (PRS) Score to the Average Pain Rating Scale Score During…