Phase 3 N=699 Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)
Diabetes Mellitus, Type II
Primary: Treatment Failure (Loss of Glycemic Control) — 120; 90; 109; 112 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=394 A Study of LY2189265 in Japanese Participants With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus
Primary: Percentage of Participants With Treatment-Emergent Adverse Events (TEAEs) — 85.5; 83.6; 70.8; 80.3 percentage of participants
Phase 1 N=20 Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Metformin in Healthy Volunteers
Neuropathic Pain
Primary: Cmax - Maximum Observed Plasma Concentration — 1091; 1224 ng/mL
N/A N=129 Treatment for Veterans With Military Sexual Trauma
Stress Disorders, Post-Traumatic · Depressive Symptoms · Anxiety Symptoms
Primary: PTSD Checklist (PCL) — 65.53; 65.40; 51.39; 57.89 units on a scale
Phase 4 N=29 Measuring Smoking Behaviors While Using Varenicline
Nicotine Dependence
Primary: Smoking Topography: Total Puff Volume — 523.4; 684.6 milliliters
N/A N=112 Resident Supervision Index: Assessing Feasibility and Validity
Healthy
Primary: Intraclass Correlation Coefficient Between Physician Resident and Attending Physician. — .69 Intraclass Correlation Coefficient
N/A N=12 Spironolactone in Patients With Single Ventricle Heart
Congenital Disorders
Primary: Change in Flow Mediated Dilation — 5.5 Percentage of brachial artery diameter
N/A N=53 Evaluating a Telehealth Treatment for Veterans With Hepatitis C and PTSD
Chronic Disease · Hepatitis C · Stress Disorders, Post-Traumatic
Primary: Hepatitis C Virus Knowledge Questionnaire — 37.88; 40.50; 35.80; 45.38 units on a scale
N/A N=28 Measures of Gait Efficiency of Three Multi-Axial, Vertical Shock and Energy Storing-Return Prosthetic Feet During Simple & Complex Mobility Activities
Amputation
Primary: Obstacle Course Completion Time — 425; 444; 419; 287 seconds
N/A N=65 Supplemental Nicotine Administration for Smoking Cessation in Posttraumatic Stress Disorder (PTSD)
Smoking Cessation
Primary: Participants Self-reporting Abstinence During 6 Weeks Post Quit — 16; 13 participants
N/A N=49 Family Networks Project Study One: An Efficacy Study of Stepping Stones Triple P for Children Under Age Two
Prevent Child Maltreatment
Primary: Parenting Style — 2.65; 2.61; 2.09; 2.21 scores on a scale
Phase 2 N=80 A Study of Belinostat + Carboplatin or Paclitaxel or Both in Patients With Ovarian Cancer in Need of Relapse Treatment
Ovarian Cancer · Epithelial Ovarian Cancer · Fallopian Tube Cancer
Primary: Maximum Tolerable Dose (MTD) Belinostat, Part A, — 1000 mg/m2
N/A N=126 Teen Asthma Project
Asthma
Primary: Pediatric Asthma Quality of Life Questionnaire (PAQLQ) — 140.30; 125.12; 138.11 units on a scale
N/A N=392 Impact of Teledermatology on Health Services Outcomes in the Department of Veterans Affairs
Skin Diseases · Telemedicine · Quality of Life
Primary: Skindex-16 Change Scores Between Baseline to Month 9 - Composite Score — -12.0; -13.2 units on a scale — p=0.66
N/A N=50 Brain Imaging Techniques That Predict Antidepressant Responsiveness
Major Depressive Disorder
Primary: Hamilton Depression (HAM-D) and Anxiety (HAM-A) Rating Scales — 20.07; 21.36; 1; 14.07 units on a scale