Phase 4 N=70 Effectiveness of Armodafinil for Treating Fatigue in Adults With HIV/AIDS
HIV Infections · Fatigue
Primary: Fatigue Severity Scale(FSS) Outcome — 52.6; 53.1; 25.8; 39.4 units on a scale — p=<0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=949 Flibanserin for the Treatment of Hypoactive Sexual Desire Disorder in Postmenopausal Women
Sexual Dysfunctions, Psychological
Primary: Change From Baseline in the Number of Satisfying Sexual Events — 1.0; 0.6 sexual events
N/A N=33 Effect of Laser Use on Guided Tissue Regeneration in Treatment of Molar Teeth With Class 2 Furcation Affected by Periodontitis
Furcation Defects · Periodontitis · Alveolar Bone Loss Beyond Furcation
Primary: Change in Clinical Attachment( Gain or Loss) Measured by Horizontal Clinical Attachment Loss(in mm) From Baseline to 6 Months. — -.82; -1.26 mm
N/A N=130 Quality of Life During Treatment of Chronic Hepatitis C (P05278/MK-4031-336)
Hepatitis C, Chronic · Genotype 1 · HCV-1
Primary: Change From Baseline (BL) to Week 72 (WK72) in 36-Item Short-Form Health Survey (SF-36) Scores — 87.27; 87.33; -1.56; 81.71 score on a scale
Phase 2 N=18 Efficacy and Safety Study of Fostamatinib Disodium Tablets to Treat T-Cell Lymphoma
T Cell Lymphoma
Primary: The Primary Efficacy Endpoint for This Study is Overall Regressive Response Rate (ORRR): Proportion of Patients With a Best Response of Complete Response (CR), Partial…
Phase 4 N=396 TReatment of Atrial Fibrillation With Dual dEfibrillator in Heart Failure Patients
Heart Failure, Congestive
Primary: Unplanned Hospital Admissions for Cardiac Reasons OR Death of Cardiovascular Causes OR Progression to Chronic Atrial Fibrillation — 43; 44 participants
Phase 1 N=24 A Study to Evaluate and Compare the Efficacy and Pharmacokinetics of MK-0873 for the Treatment of Plaque Psoriasis (MK-0873-022)
Psoriasis · Plaque Psoriasis
Primary: Least Squares Mean Percent Change From Baseline (Predose Day 1) of Target Lesion Severity (TLS) Score for Lesions Treated With MK-0873 and Lesions Treated With MK-0873…
N/A N=12 Magnetic Resonance Spectroscopy Imaging in Predicting Response to Vorinostat and Temozolomide in Patients With Recurrent or Progressive Glioblastoma
Adult Glioblastoma · Depression · Recurrent Adult Brain Tumor
Primary: Proportion of Patients With Magnetic Resonance Spectroscopy (MRS) Response to Initial Vorinostat by MRI and MRS Scans as Determined by Spectroscopic Index — 0 participants
N/A N=99 Approaches to Auditory Rehabilitation for Mild Traumatic Brain Injury
Traumatic Brain Injury
Primary: Competence Score From the Psychosocial Impact of Assistive Devices Scale (PIADS) — 0.56; .37; .62; .41 units on a scale — p=0.527
N/A N=37 Effectiveness of Cognitive Remediation in a Supported Education Setting
Psychosis
Primary: Completion of Academic Semesters — 1.95; 1.67; 1.89; 1.67 Courses completed — p=0.029
N/A N=211 Comparison Between Internal and External Preoperative Biliary Drainage in Periampullary Cancers
Periampullary Cancers With Obstructive Jaundice · Pancreas Head Cancer · Bile Duct Cancer
Primary: Incidence of Infectious Complications After Biliary Drainage — 11; 5 participants
N/A N=100 The Effect of Transcutaneous Electrical Nerve Stimulation on Posterior Neck Pain After Thyroidectomy
Thyroid Cancer · Neck Pain
Primary: Numerical Rating Scale of Posterior Neck Pain 0.5 Hours After Thyroidectomy — 3.5; 0; 3.5; 0 scores on a scale
Phase 1 N=24 A Study to Evaluate the PK/PD and Safety of TA-7284 in Patients With Type 2 Diabetes Mellitus Who Have Moderate Renal Impairment
Type 2 Diabetes Mellitus
Primary: Effect of Renal Function on Maximum Plasma Concentration of TA-7284 — 1197.1264; 2333.3617; 1213.6571; 2415.6109 ng / mL
N/A N=40 Effect of Phytosterols on Nonalcoholic Fatty Liver Disease
Non-alcoholic Fatty Liver Disease
Primary: Metabolic Effect of Phytosterols on Patients With Nonalcoholic Fatty Liver Disease — 184.1; 191.65; 174.60; 199.25 mg/dl — p=<0.05
Phase 4 N=1,166 MINERVA: MINimizE Right Ventricular Pacing to Prevent Atrial Fibrillation and Heart Failure
Atrial Fibrillation · Heart Failure, Congestive
Primary: Composite Endpoint Composed by Death for Any Cause, Cardiovascular Hospitalization or Permanent AF at 2 Years — 28.0; 23.1; 21.5 percentage of participants