65,437 trials
Diabetic Macular Edema
Primary: The Primary Objective of the Study is to Evaluate the Ocular Safety and Tolerability (by Incidence of Ocular Adverse Events) of EXN407 Ophthalmic Solution in Dose…
Carcinoma, Small Cell · Lung Cancer · Small Cell Lung Cancer
Primary: Proportion of Evaluable Participants Who Experience a Partial Response (PR) or Complete Response (CR) Reported Along With an 80% Confidence Interval. — 0.1; 0; 0.2; 0…
Venous Leg Ulcer · Mixed Leg Ulcer
Primary: Percentage Change of the Wound Area — 42.41; 60.75; 25.18; 72.16 percentage of change
Alcohol Use Disorder
Primary: Change in Heavy Drinking Days Per Week for Dutasteride vs. Placebo Groups — -2.24; -1.41 Heavy Drinking Days per week — p=0.012
Motion Sickness
Primary: The Most Severe Motion Sickness Severity During Vehicle Travel — 3.4; 3.75 units on a scale
Arthralgia · Breast Cancer
Primary: Absolute Change in Brief Pain Inventory (BPI) Worst Pain From Baseline to Week 15 — -2.4 units on a scale
Autism Spectrum Disorder
Primary: Change in Mitochondrial Activity in Study Patients: Citrate Synthase — 40.56; 29.09; 27.41; 37.78 nmoles/min/mg protein
Gastroenteritis
Primary: Percentage of Participants With Anti-rotavirus (RV) Immunoglobulin A (IgA) Antibody (Ab) Seroconversion Rate — 88.7; 84.9 Percentage of participants
Traumatic Brain Injury (TBI) · Chronic Traumatic Encephalopathy (CTE)
Primary: Changes in Brain Biomarkers Due to Sub-concussion Injury - Nf-L — 5.36; 4.82; 6.05; 6.47 pg/ml
Dengue Disease · Dengue Virus
Primary: Dengue Virus-Neutralizing Antibody Titers, as Measured by Virus Reduction Neutralization Test (VRNT) — 326.31; 261.10; 184.85; 10.33 Titer
Non-small Cell Lung Cancer
Primary: Intracranial Objective Response Rate — 6; 0; 5; 0 Participants
Guilt · Shame · Post-traumatic Stress Disorders
Primary: Trauma Related Guilt Inventory - Guilt Severity — 2.5; 2.5; 1.6; 2.2 score on a scale
Food Allergy
Primary: Desensitisation — 7; 5; 2 Participants
Cognition Disorder · Stroke · Occlusion Carotid
Primary: Change in Montreal Cognitive Assessment (MoCA) Score — 0.56; 1.38; -0.75; 0.50 score on a scale
Environmental Exposure
Primary: Peak Plasma Concentration of 14C-BaP Cmax — 3.69; 1.67; 0.68 fg [14C]-BaP/mL plasma