N/A N=739 Impact of Sperm DNA Integrity on In Vitro Cycles
Male Infertility · Unexplained Infertility · Abortion, Habitual
Primary: Pregnancy — 67; 80 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=560 Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension
Open-Angle Glaucoma · Ocular Hypertension
Primary: Mean Diurnal IOP Change From Baseline at Month 3 — -7.9; -6.5; -6.4 millimeters of mercury (mmHg)
Phase 4 N=29 Vasoconstrictors as Alternatives to Albumin After Large-Volume Paracentesis (LVP) in Cirrhosis
Ascites · Cirrhosis
Primary: Time to Recurrence of Ascites. — 10; 8 days — p=<0.05
Phase 2 N=44 A Placebo-Controlled Study of Clonidine for Fecal Incontinence.
Fecal Incontinence
Primary: Mean Fecal Incontinence and Constipation Assessment (FICA) Score — 8.1; 9.1; 6.5; 7.6 units on a scale
N/A N=7,740 DELIVER Study: DELiverability of the Resolute Integrity Stent in All-Comer Vessels and Cross-OvER Stenting
Coronary Artery Disease
Primary: Delivery Success — 10617 stents
Phase 1 N=75 Comparison of Ipilimumab Manufactured by 2 Different Processes in Participants With Advanced Melanoma
Advanced Melanoma
Primary: Maximum Observed Serum Concentration (Cmax) of Ipilimumab Manufactured by Process C Relative to the Cmax of Ipilimumab Manufactured by Process B - Evaluable…
N/A N=61 Evaluation of Comfilcon A and Senofilcon A Lenses
Myopia
Primary: Subjective Responses for Comfort Rated on a 0-100 Visual Scale. — 86; 87; 89; 91 units on a scale
Phase 3 N=44 Safety and Efficacy of the GTS400 Stent in Conjunction With Cataract
Open-angle Glaucoma
Primary: Month 12 Intraocular Pressure ≤ 18 mmHg Without Topical Hypotensive Medications — 18; 4 participants
Phase 2 N=5 A Study of Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer Receiving Postoperative Radiotherapy and Concurrent Chemotherapy
Mucositis · Head and Neck Cancer
Primary: Number of Participants With Adverse Events (AEs) — 2; 3; 0; 2 participants
Phase 4 N=49 A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B501
Retraction of Colostomy
Primary: Total Opioid Burden — 67.7; 38.41 mg morphine equivalent
N/A N=49 Proclear 1-D Multifocal Nondispensing Study
Presbyopia
Primary: Objective Vision Assessments: High Contrast Distance Visual Acuity — -0.09; -0.05 logMAR units
Phase 2 N=51 Effect of Vitamin D3 Supplementation on Insulin Resistance and Cardiovascular Risk Factors in Obese Adolescents
Obesity
Primary: Change in Insulin Resistance After 12 Weeks of Vitamin D3 Supplementation — 0.01; -0.27 HOMA score — p=0.95
N/A N=8,790 Retrospective Record Review of Adults and Children Advised for Allergen Immunotherapy (MK-7243-022)
Perennial Allergic Rhinitis · Seasonal Allergic Rhinitis
Primary: Percentage of Participants Advised to Start AIT Who Elected Subcutaneous Immunotherapy (SCIT) Shots or Sublingual Immunotherapy (SLIT) Drops — 28.2; 8.0 percentage of…
Phase 2 N=95 Study to Evaluate Palifermin in the Reduction of Dysphagia in Patients With Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
Dysphagia · Non-Small Cell Lung Cancer · Lung Cancer
Primary: Number of Participants With Grade 2 or Higher Dysphagia — 32; 30; 13; 18 participants — p=0.3550
Phase 4 N=387 Phase 4 Study to Evaluate Efficacy of Paliperidone Extended-Release(ER) in Schizophrenic Participants
Schizophrenia
Primary: Change From Baseline in Symptom Checklist 90-R (SCL90-R) at Week 24 — 99.84; 73.03; 67.66; 13.09 Units on a scale